Scutellarin alleviates lipopolysaccharide-provoked septic nephrotoxicity via attenuation of inflammatory and oxidative events and mitochondrial dysfunction
A Shahmohammadi, R Golchoobian… - …, 2023 - Taylor & Francis
Background Sepsis-associated acute kidney injury (AKI) is highlighted by high incidence of
mortality and morbidity. Scutellarin is a flavone extracted from certain medicinal plants with …
mortality and morbidity. Scutellarin is a flavone extracted from certain medicinal plants with …
Circ_0002131 contributes to LPS-induced apoptosis, inflammation, and oxidative injury in Hk-2 cells via inhibiting the binding between Mir-942-5p and Oxsr1
P Zhang, J Yin, L Xun, T Ding, S Du - Shock, 2023 - journals.lww.com
Background: Circular RNAs are implicated in the progression of sepsis-associated acute
kidney injury (AKI). Circ_0002131 was shown to aggravate cell inflammation and oxidative …
kidney injury (AKI). Circ_0002131 was shown to aggravate cell inflammation and oxidative …
Inhibition of Xanthine Oxidase Protects against Sepsis‐Induced Acute Kidney Injury by Ameliorating Renal Hypoxia
T Wang, Y Du, W Wang, X Li… - Oxidative Medicine and …, 2022 - Wiley Online Library
Xanthine oxidase (XO) utilizes molecular oxygen as a substrate to convert purine substrates
into uric acid, superoxide, and hydrogen peroxide, which is one of the main enzyme …
into uric acid, superoxide, and hydrogen peroxide, which is one of the main enzyme …
Drugs in treating paediatric acute kidney injury
C Costigan, S Balgobin, M Zappitelli - Pediatric Nephrology, 2023 - Springer
Acute kidney injury (AKI) is a complex syndrome which affects a significant proportion of
hospitalized children. The breadth and impact of AKI on health outcomes in both adults and …
hospitalized children. The breadth and impact of AKI on health outcomes in both adults and …
MicroRNA‑17‑5p alleviates sepsis‑related acute kidney injury in mice by modulating inflammation and apoptosis
J Sun, L Niu, Y Wang, G Zhao… - Molecular …, 2024 - spandidos-publications.com
Septic acute kidney injury (AKI) is considered as a severe and frequent complication that
occurs during sepsis. Mounting evidence has confirmed the pivotal pathogenetic roles of …
occurs during sepsis. Mounting evidence has confirmed the pivotal pathogenetic roles of …
Genkwanin improves inflammatory injury in rats with septic lung injury by regulating NF-κB signaling pathway
G Qin, S Yi - Quality Assurance and Safety of Crops & Foods, 2022 - qascf.com
To assess possible effects of genkwanin (GKA) in septic lung injury and its related
mechanisms. An animal model of cecal ligation and puncture (CLP)-induced acute lung …
mechanisms. An animal model of cecal ligation and puncture (CLP)-induced acute lung …
PHLDA1 knockdown inhibits inflammation and oxidative stress by regulating JNK/ERK pathway, and plays a protective role in sepsis-induced acute kidney injury
M Gong, W Liang, Q Lu, J Zhang - Allergologia et Immunopathologia, 2022 - all-imm.com
Background: Acute kidney injury (AKI), a prevalent complication of sepsis, causes
substantial burden on patients' families as well as the society. More reliable markers are …
substantial burden on patients' families as well as the society. More reliable markers are …
Knockdown of P2Y4 ameliorates sepsis-induced acute kidney injury in mice via inhibiting the activation of the NF-κB/MMP8 axis
M Wang, F Jiang, L Zhang, J Zhang, H Xie - Frontiers in Physiology, 2022 - frontiersin.org
Sepsis-induced acute kidney injury (S-AKI) has emerged as a frequent and life-threatening
complication in critically ill patients, which is characterized by a systematic inflammatory …
complication in critically ill patients, which is characterized by a systematic inflammatory …
[HTML][HTML] S-Nitrosoglutathione protects acute kidney injury in septic rats by inhibiting the activation of NLRP3 inflammasome
H Fan, M Sun, J Le, J Zhu - Iranian Journal of Basic Medical …, 2023 - ncbi.nlm.nih.gov
Objective (s): We aimed to study the effect of S-nitroso glutathione (SNG) on acute kidney
injury (AKI) in septic rats by regulating nucleotide oligomerization domain-like receptor …
injury (AKI) in septic rats by regulating nucleotide oligomerization domain-like receptor …