Prior to the introduction of rotavirus vaccines in 2006, rotavirus was the leading cause of
severe gastroenteritis among European children< 5 years of age. We conducted a …

Introduction: Prior to 2006, nearly every US child was infected with rotavirus by 5 years of
age, and rotavirus was the leading cause of severe childhood gastroenteritis. In February …

Background Despite the success of rotavirus vaccines, suboptimal vaccine efficacy in
regions with a high burden of disease continues to present a challenge to worldwide …

Background: Postlicensure surveillance studies suggest a small temporal increase in the
risk for intussusception with both currently available rotavirus vaccines (RV1; Rotarix, GSK …

Since the first licensure of the Sabin oral polio vaccine more than 50 years ago, only eight
enteric vaccines have been licensed for four disease indications, and all are given orally …

Oral rotavirus vaccines were incorporated into the National Immunisation Program (NIP) for
all Australian infants in July 2007. Initially each of the eight jurisdictions implemented Rotarix …

The development and widespread use of vaccination over the past centuries has been the
single most impactful intervention in public health, by effectively preventing morbidity and …

Introduction Rotavirus is the leading cause of acute diarrhea among children< 5 years
worldwide. As all children are equally susceptible to infection and disease development …

Background and objective Since 2013, a biennial rotavirus pattern has emerged in the
Netherlands with alternating high and low endemic years and a nearly 50% reduction in …

By January 2015, rotavirus vaccination had been implemented in national vaccination
programmes in 75 countries worldwide. Two live oral rotavirus vaccines are internationally …