Therapy-resistant viral reactivations contribute significantly to mortality after hematopoietic
stem cell transplantation. Adoptive cellular therapy with virus-specific T cells (VST) has …

Chimeric antigen receptor (CAR) T cell therapy represents a major breakthrough in the field
of immuno‐oncology. Many potential issues are apparent for autologous CAR T cell therapy …

Cytomegalovirus (CMV) infection/reactivation remains among the most important
complications of immunosuppression after transplantation. However, recent clinical …

Background The adoptive transfer of allogeneic antiviral T lymphocytes derived from
seropositive donors can safely and effectively reduce or prevent the clinical manifestation of …

CD8+ T cells play an important role in protection against viral infections. With age, changes
in the T-cell pool occur, leading to diminished responses against both new and recurring …

Adoptive immunotherapy with donor-derived antiviral T cells can prevent viral complications
such as with cytomegalovirus (CMV) and Epstein–Barr virus (EBV). In this context accurate …

Older adults often show signs of impaired CD8+ T‐cell immunity, reflected by weaker
responses against new infections and vaccinations, and decreased protection against …

Complete donor chimerism is strongly associated with complete remission after allogeneic
stem cell transplantation (allo-SCT) in patients with hematologic malignancies. Donor …

Introduction Aspergillus fumigatus (Asp) infections constitute a major cause of morbidity and
mortality in patients following allogeneic hematopoietic stem cell transplantation (HSCT). In …

Approximately, up to 70% of the human population is infected with cytomegalovirus (CMV)
that persists for life in a latent state. In healthy people, CMV reactivation induces the …