[HTML][HTML] Use of direct oral anticoagulants in patients with obesity for treatment and prevention of venous thromboembolism: updated communication from the ISTH …

KA Martin, J Beyer‐Westendorf, BL Davidson… - Journal of thrombosis …, 2021 - Elsevier
Although direct‐acting oral anticoagulants (DOACs) have widespread first‐line use for
treatment and prevention of venous thromboembolism (VTE), uncertainty remains regarding …

Direct oral anticoagulant use: a practical guide to common clinical challenges

A Chen, E Stecker, B A. Warden - Journal of the American Heart …, 2020 - Am Heart Assoc
Direct oral anticoagulants (DOAC s) have quickly become attractive alternatives to the long‐
standing standard of care in anticoagulation, vitamin K antagonist. DOAC s are indicated for …

Laboratory monitoring of direct oral anticoagulants (DOACs)

C Dunois - Biomedicines, 2021 - mdpi.com
The introduction of direct oral anticoagulants (DOACs), such as dabigatran, rivaroxaban,
apixaban, edoxaban, and betrixaban, provides safe and effective alternative to previous …

Challenges in Cardiovascular Evaluation and Management of Obese Patients: JACC State-of-the-Art Review

RG Bianchettin, CJ Lavie, F Lopez-Jimenez - Journal of the American …, 2023 - jacc.org
Many unique clinical challenges accompany the diagnosis and treatment of cardiovascular
disease (CVD) in people living with overweight/obesity. Similarly, physicians encounter …

Comparative effectiveness and safety of direct oral anticoagulants compared to warfarin in morbidly obese patients with acute venous thromboembolism: systematic …

MN Elshafei, MFH Mohamed, A El-Bardissy… - Journal of thrombosis …, 2021 - Springer
Direct oral anticoagulant (DOAC) agents are becoming the anticoagulation strategy of
choice. However, their use in the treatment of acute venous thromboembolism (VTE) in …

The Role of Biomarkers, Metabolomics, and COVID-19 in Venous Thromboembolism—A Review of Literature

V Della Corte, R Riolo, S Scaglione… - International Journal of …, 2023 - mdpi.com
In recent years, the field of venous thromboembolism has undergone numerous innovations,
starting from the recent discoveries on the role of biomarkers, passing through the role of …

Effectiveness and safety of apixaban vs. warfarin in venous thromboembolism patients with obesity and morbid obesity

A Cohen, J Sah, T Lee, L Rosenblatt… - Journal of Clinical …, 2021 - mdpi.com
This study integrated 5 United States healthcare claims databases to evaluate the risk of
recurrent venous thromboembolism (VTE) and major bleeding (MB) among VTE patients …

Direct oral anticoagulants in obesity: an updated literature review

J Sebaaly, D Kelley - Annals of Pharmacotherapy, 2020 - journals.sagepub.com
Objective: To review literature on the use of direct-acting oral anticoagulants (DOACs) in
patients with high body weight (BW) and/or high body mass index (BMI) and to make …

Efficacy, safety, and exposure of apixaban in patients with high body weight or obesity and venous thromboembolism: insights from AMPLIFY

AT Cohen, S Pan, W Byon, BS Ilyas, T Taylor… - Advances in Therapy, 2021 - Springer
Introduction As a result of limited clinical data, guidelines do not recommend the use of non-
vitamin K antagonist oral anticoagulants in patients who weigh> 120 kg or have a body …

Apixaban and rivaroxaban in obese patients treated for venous thromboembolism: drug levels and clinical outcomes

A Ballerie, RN Van, K Lacut, H Galinat, C Rousseau… - Thrombosis research, 2021 - Elsevier
Background Direct oral anticoagulants (DOAC) use remains challenging in obese patients
treated for Venous-Thrombo-Embolism (VTE) due to the paucity of prospective and …