Immunosuppressive drugs and fertility

C Leroy, JM Rigot, M Leroy, C Decanter… - Orphanet journal of rare …, 2015 - Springer
Immunosuppressive drugs are used in the treatment of inflammatory and autoimmune
diseases, as well as in transplantation. Frequently prescribed in young people, these …

AGA technical review on the management of mild-to-moderate ulcerative colitis

S Singh, JD Feuerstein, DG Binion, WJ Tremaine - Gastroenterology, 2019 - Elsevier
Most patients with ulcerative colitis (UC) have mild-to-moderate disease activity, with low risk
of colectomy, and are managed by primary care physicians or gastroenterologists. Optimal …

European Crohn's and colitis guidelines on sexuality, fertility, pregnancy, and lactation

J Torres, M Chaparro, M Julsgaard… - Journal of Crohn's …, 2023 - academic.oup.com
2. Methods This document represents the third version of the European Consensus on
reproduction in IBD. The development of this Consensus included the formulation of …

BSR and BHPR guideline on prescribing drugs in pregnancy and breastfeeding—Part I: standard and biologic disease modifying anti-rheumatic drugs and …

J Flint, S Panchal, A Hurrell, M van de Venne… - …, 2016 - academic.oup.com
Julia Flint1, Sonia Panchal2, Alice Hurrell3, Maud van de Venne4, Mary Gayed5, Karen
Schreiber6, 7, Subha Arthanari8, Joel Cunningham3, Lucy Flanders3, Louise Moore9, Amy …

East–West gradient in the incidence of inflammatory bowel disease in Europe: the ECCO-EpiCom inception cohort

J Burisch, N Pedersen, S Čuković-Čavka, M Brinar… - Gut, 2014 - gut.bmj.com
Objective The incidence of inflammatory bowel disease (IBD) is increasing in Eastern
Europe. The reasons for these changes remain unknown. The aim of this study was to …

Long-term safety ofin uteroexposure to anti-TNFα drugs for the treatment of inflammatory bowel disease: Results from the multicenter European TEDDY study

M Chaparro, A Verreth, T Lobaton… - Official journal of the …, 2018 - journals.lww.com
OBJECTIVES: The long-term safety of exposure to anti-tumor necrosis factor (anti-TNFα)
drugs during pregnancy has received little attention. We aimed to compare the relative risk …

Meta‐analysis: the impact of disease activity at conception on disease activity during pregnancy in patients with inflammatory bowel disease

A Abhyankar, M Ham, AC Moss - Alimentary pharmacology & …, 2013 - Wiley Online Library
Background The rate of exacerbation of inflammatory bowel disease (IBD) during pregnancy
varies in the published literature. Aim We sought to perform a systematic review and meta …

Vedolizumab exposure in pregnancy: outcomes from clinical studies in inflammatory bowel disease

U Mahadevan, S Vermeire, K Lasch… - Alimentary …, 2017 - Wiley Online Library
Background Vedolizumab is a gut‐selective immunoglobulin G1 monoclonal antibody to
α4β7 integrin for the treatment of Crohn's disease (CD) and ulcerative colitis (UC) …

Targeting TNF-α for the treatment of inflammatory bowel disease

T Billiet, P Rutgeerts, M Ferrante… - Expert opinion on …, 2014 - Taylor & Francis
Introduction: The advent of tumor necrosis factor (TNF) antagonists represented a radical
change in the management of inflammatory bowel disease (IBD). Both in short-and long …

Crohn's disease

R Kalla, NT Ventham, J Satsangi, IDR Arnott - Bmj, 2014 - bmj.com
Crohn's disease is a chronic inflammatory disorder that can affect any part of the
gastrointestinal tract. Although the disease most commonly presents at a young age, it can …