[HTML][HTML] Alzheimer's disease current therapies, novel drug delivery systems and future directions for better disease management
Abstract Alzheimer's disease (AD), is a neurodegenerative disorder that escalates with time,
exerting a significant impact on physical and mental health and leading to death. The …
exerting a significant impact on physical and mental health and leading to death. The …
Current state and opportunities with long-acting injectables: industry perspectives from the innovation and quality consortium “long-acting injectables” working group
A Bauer, P Berben, SS Chakravarthi… - Pharmaceutical …, 2023 - Springer
Long-acting injectable (LAI) formulations can provide several advantages over the more
traditional oral formulation as drug product opportunities. LAI formulations can achieve …
traditional oral formulation as drug product opportunities. LAI formulations can achieve …
Oral drug delivery systems applied to launched products: value for the patients and industrial considerations
T Yoshida, H Kojima - Molecular Pharmaceutics, 2023 - ACS Publications
Drug delivery systems (DDS) control the amount, rate, and site of administration of drug
substances in the body as well as their release and ADME (absorption, distribution …
substances in the body as well as their release and ADME (absorption, distribution …
Polyester-based long acting injectables: advancements in molecular dynamics simulation and technological insights
Highlights•Polyesters including poly (lactic-co-glycolic acid)(PLGA) are promising polymers
for long-acting injectable (LAI) drug delivery. LAIs release the active pharmaceutical …
for long-acting injectable (LAI) drug delivery. LAIs release the active pharmaceutical …
Role of modeling and simulation in preclinical and clinical long-acting injectable drug development
Innovations in the field of long-acting injectable drug development are increasingly being
reported. More advanced in vitro and in vivo characterization can improve our …
reported. More advanced in vitro and in vivo characterization can improve our …
Long-acting injectable aqueous suspensions—summary from an AAPS Workshop
Through many years of clinical application of long-acting injectables, there is clear proof that
this type of formulation does not just provide the patient with convenience, but more …
this type of formulation does not just provide the patient with convenience, but more …
Polymers and their engineered analogues for ocular drug delivery: Enhancing therapeutic precision
A Biswas, S Kumar, AD Choudhury, AC Bisen… - …, 2024 - Wiley Online Library
Ocular drug delivery is constrained by anatomical and physiological barriers, necessitating
innovative solutions for effective therapy. Natural polymers like hyaluronic acid, chitosan …
innovative solutions for effective therapy. Natural polymers like hyaluronic acid, chitosan …
Long acting injectables for the treatment of prostate cancer
D Modi, MS Hussain, S Ainampudi… - Journal of Drug Delivery …, 2024 - Elsevier
Prostate cancer ranks as one of the most diagnosed and challenging malignancies affecting
individuals worldwide. For hormone-dependent prostate cancer treatment Gonadotropin …
individuals worldwide. For hormone-dependent prostate cancer treatment Gonadotropin …
Folic Acid-Decorated Nanocrystals as Highly Loaded Trojan Horses to Target Cancer Cells
The nanocrystal (NC) technology has become one of the most commonly used strategies for
the formulation of poorly soluble actives. Given their large specific surface, NCs are mainly …
the formulation of poorly soluble actives. Given their large specific surface, NCs are mainly …
Patient-Centric Long-Acting Injectable and Implantable Platforms─ An Industrial Perspective
S Alidori, R Subramanian, R Holm - Molecular Pharmaceutics, 2024 - ACS Publications
The increasing focus on patient centricity in the pharmaceutical industry over the past
decade and the changing healthcare landscape, driven by factors such as increased access …
decade and the changing healthcare landscape, driven by factors such as increased access …