Advances in preclinical PET

SS Adler, J Seidel, PL Choyke - Seminars in nuclear medicine, 2022 - Elsevier
The classical intent of PET imaging is to obtain the most accurate estimate of the amount of
positron-emitting radiotracer in the smallest possible volume element located anywhere in …

Comparison of image quality and spatial resolution between 18F, 68Ga, and 64Cu phantom measurements using a digital Biograph Vision PET/CT

A Braune, L Oehme, R Freudenberg, F Hofheinz… - EJNMMI physics, 2022 - Springer
Background PET nuclides can have a considerable influence on the spatial resolution and
image quality of PET/CT scans, which can influence diagnostics in oncology, for example …

[HTML][HTML] Implementation of a spatially-variant and tissue-dependent positron range correction for PET/CT imaging

H Kertész, T Beyer, V Panin, W Jentzen… - Frontiers in …, 2022 - frontiersin.org
Aim To develop and evaluate a new approach for spatially variant and tissue-dependent
positron range (PR) correction (PRC) during the iterative PET image reconstruction …

Evaluation of image quality with four positron emitters and three preclinical PET/CT systems

J Teuho, L Riehakainen, A Honkaniemi, O Moisio… - EJNMMI research, 2020 - Springer
Background We investigated the image quality of 11 C, 68 Ga, 18 F and 89 Zr, which have
different positron fractions, physical half-lifes and positron ranges. Three small animal …

Development of a CD163-targeted pet radiotracer that images resident macrophages in atherosclerosis

X Zhang, GS Heo, A Li, D Lahad… - Journal of Nuclear …, 2024 - Soc Nuclear Med
Tissue-resident macrophages are complementary to proinflammatory macrophages to
promote the progression of atherosclerosis. The noninvasive detection of their presence and …

Monte Carlo simulations of the GE Signa PET/MR for different radioisotopes

PRRV Caribé, S Vandenberghe, A Diogo… - Frontiers in …, 2020 - frontiersin.org
NEMA characterization of PET systems is generally based on 18F because it is the most
relevant radioisotope for the clinical use of PET. 18F has a half-life of 109.7 min and decays …

Performance evaluation of iterative PET reconstruction with resolution recovery incorporating Gallium‐68 positron range correction

P Gavriilidis, M Koole, A Marinus, FP Jansen… - Medical …, 2024 - Wiley Online Library
Background The distance traveled by the positron before annihilation with an electron, the
so‐called positron range, negatively effects the positron emission tomography (PET) image …

Feasibility of positron range correction in 82-Rubidium cardiac PET/CT

M Jensen, S Bentsen, A Clemmensen, JK Jensen… - EJNMMI physics, 2022 - Springer
Background Myocardial perfusion imaging (MPI) using positron emission tomography (PET)
tracers is an essential tool in investigating diseases and treatment responses in cardiology …

Characterization of the BOLDPET optical prototype, an innovative Cherenkov detector for 511 keV radiation

R Chyzh, G Tauzin, D Yvon, CH Sung, D Breton… - arXiv preprint arXiv …, 2024 - arxiv.org
In the present work we describe the design, construction, and testing of the optical prototype
developed for the BOLDPET project, with the objective of creating a PET detection module …

Preliminary investigation of the impact of axial ring splitting on image quality for the cost reduction of total-body PET

N Efthimiou, AC Whitehead, M Stockhoff… - 2019 IEEE Nuclear …, 2019 - ieeexplore.ieee.org
Recently, the first TB-PET scanner was unveiled and the initial results were nevertheless
impressive. However, the cost of a TB-PET scanner is prohibiting for many institutions …