Epigenetic factors, such as DNA methylation, play an influential role in the development of
the degenerative joint disease osteoarthritis (OA). These molecular mechanisms have been …

In this paper, we propose techniques for securing Software Defined Networks (SDN). We
describe the design of a security architecture that makes use of security applications on top …

Genome-wide expression and methylation profiling reveal candidate genes in osteoarthritis
Page 1 Clinical and Experimental Rheumatology 2017 Clinical and Experimental …

Background Researches indicate that epigenetics was involved in osteoarthritis (OA). The
purpose of this study was to describe the alterations of DNA methylation in hip and knee OA …

The epigenome is a dynamic system of chemical modifications that operate to control
chromatin structure and regulate gene activity without altering the underlying DNA …

Background This study aimed to explore potential novel genes correlated with osteoarthritis
(OA). Methods The gene expression profile of GSE48422 was downloaded from the Gene …

A general analytical framework is described for melding graph-theoretical algorithms and
machine learning technologies. A main goal is to extract latent relationships and other forms …

Osteoarthritis (OA) is a chronic, degenerative, musculoskeletal disease that is the leading
cause of disability in the United States. OA affects over 32 million adults in the US resulting …

Many skeletal and mineral metabolic diseases have a genetic basis, which may be a
germline single gene abnormality (ie, a monogenic or Mendelian disorder), a somatic single …

Method: Twenty-four synovial tissue samples were selected. OA synovial tissue samples
were obtained from 10 Tibetan OA patients at high altitude and 8 Han OA patients at low …