Polycyclic aromatic hydrocarbon and its effects on human health: An overeview
MA Mallah, L Changxing, MA Mallah, S Noreen, Y Liu… - Chemosphere, 2022 - Elsevier
Polycyclic aromatic hydrocarbons (PAHs) are a class of chemicals of considerable
environmental significance. PAHs are chemical contaminants of fused carbon and hydrogen …
environmental significance. PAHs are chemical contaminants of fused carbon and hydrogen …
[HTML][HTML] Potential role of polycyclic aromatic hydrocarbons in air pollution-induced non-malignant respiratory diseases
Epidemiological studies have found strong associations between air pollution and
respiratory effects including development and/or exacerbation of asthma and chronic …
respiratory effects including development and/or exacerbation of asthma and chronic …
[HTML][HTML] Role of indoleamine 2, 3-dioxygenase 1 (IDO1) and kynurenine pathway in the regulation of the aging process
A Salminen - Ageing Research Reviews, 2022 - Elsevier
Abstract Indoleamine 2, 3-dioxygenase 1 (IDO1) is activated in chronic inflammatory states,
eg, in the aging process and age-related diseases. IDO1 enzyme catabolizes L-tryptophan …
eg, in the aging process and age-related diseases. IDO1 enzyme catabolizes L-tryptophan …
[HTML][HTML] Potential role of polycyclic aromatic hydrocarbons as mediators of cardiovascular effects from combustion particles
Air pollution is the most important environmental risk factor for disease and premature death,
and exposure to combustion particles from vehicles is a major contributor. Human …
and exposure to combustion particles from vehicles is a major contributor. Human …
[HTML][HTML] Aryl hydrocarbon receptor (AhR) reveals evidence of antagonistic pleiotropy in the regulation of the aging process
A Salminen - Cellular and Molecular Life Sciences, 2022 - Springer
The antagonistic pleiotropy hypothesis is a well-known evolutionary theory to explain the
aging process. It proposes that while a particular gene may possess beneficial effects during …
aging process. It proposes that while a particular gene may possess beneficial effects during …
[HTML][HTML] Aryl hydrocarbon receptor pathway: Role, regulation and intervention in atherosclerosis therapy
K Zhu, Q Meng, Z Zhang, T Yi… - Molecular …, 2019 - build.spandidos-publications.com
The aryl hydrocarbon receptor (AhR) is a ligand‑activated transcription factor originally
isolated and characterized as the dioxin or xenobiotic receptor. With the discovery of …
isolated and characterized as the dioxin or xenobiotic receptor. With the discovery of …
[HTML][HTML] Exposure to urban nanoparticles at low PM concentrations as a source of oxidative stress and inflammation
Exposures to fine particulate matter (PM 1) have been associated with health impacts, but
the understanding of the PM 1 concentration-response (PM 1-CR) relationships, especially …
the understanding of the PM 1 concentration-response (PM 1-CR) relationships, especially …
PM2. 5 exposure exacerbates mice thoracic aortic aneurysm and dissection by inducing smooth muscle cell apoptosis via the MAPK pathway
Y Ming, X Zhou, G Liu, M Abudupataer, S Zhu, B Xiang… - Chemosphere, 2023 - Elsevier
Air pollution is a major public health concern worldwide. Exposure to fine particulate matter
(PM2. 5) is closely associated with cardiovascular diseases. However, the effect of PM2. 5 …
(PM2. 5) is closely associated with cardiovascular diseases. However, the effect of PM2. 5 …
[HTML][HTML] Modulating AHR function offers exciting therapeutic potential in gut immunity and inflammation
Y Chen, Y Wang, Y Fu, Y Yin, K Xu - Cell & Bioscience, 2023 - Springer
Aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor. 2, 3, 7, 8-
tetrachlorodibenzo-p-dioxin (TCDD) is a classical exogenous synthetic ligand of AHR that …
tetrachlorodibenzo-p-dioxin (TCDD) is a classical exogenous synthetic ligand of AHR that …
Environmental dose of 16 priority-controlled PAHs mixture induce damages of vascular endothelial cells involved in oxidative stress and inflammation
J He, Q Pang, C Huang, J Xie, J Hu, L Wang, C Wang… - Toxicology in Vitro, 2022 - Elsevier
Epidemiological studies have shown that cardiovascular diseases caused by PM 2.5
pollution account for the second death rate in China. Polycyclic aromatic hydrocarbons …
pollution account for the second death rate in China. Polycyclic aromatic hydrocarbons …