OBJECTIVE: To assess the effect of chronic low-dose administration of tadalafil (Td) on
penile cavernous tissue in induced diabetic rats. METHODS: The study investigaged 48 …

Abstract Introduction Phosphodiesterase type 5 (PDE-5) hydrolyzes cyclic guanylate
monophosphate (cGMP) specifically to 5′ GMP, promoting successful corporeal vascular …

This study aimed to assess the effect of testosterone (T) administration and chronic low‐
dose sildenafil/tadalafil on cavernous tissue oxidative stress (OS) of aged diabetic rats. In all …

Phosphodiesterase inhibitors have been reported to be beneficial in cognitive and motor
disorders. In the present study, we have investigated the effects of RO 20-1724 (PDE4 …

ADHD Attention deficit hyperactivity disorder ART Assisted reproductive technology ASA
Antisperm antibodies BMI Body mass index BPH Benign prostate hyperplasia BTB Blood …

Abstract Phosphodiesterase 5 (PDE5) inhibitors are often used in combination with club
drugs such as 3, 4‐methylenedioxymethamphetamine (MDMA or ecstasy). We investigated …

This work aimed to assess the cavernous anti-apoptotic role of using chronic low-dose
sildenafil/tadalafil with and without testosterone (T) in aged diabetic rats. In all, 140 Sprague …

Introduction Erectile dysfunction (ED) and hypertension are frequent comorbid conditions.
The vasodilating properties of type 5 phosphodiesterase inhibitor (PDE5I) are the major …

Introduction Recurrent ischemic priapism still remains a serious and difficult to treat
complication of certain hematological disorders. Elucidation of the underlying …

Objective: The most important issue in flap surgery is flap viability. This study aimed to
compare the effects of most commonly used phosphodiesterase type 5 (PDE5) inhibitors on …