Since the 1970s, introduction of serological assays targeting virus-specific antibodies and
antigens has been effective in identifying blood donations infected with the classic …

Photodynamic therapy (PDT) is a well-established treatment option in the treatment of
certain cancerous and pre-cancerous lesions. Though best-known for its application in …

Platelet transfusions carry greater risks of infection, sepsis, and death than any other blood
product, owing primarily to bacterial contamination. Many patients may be at particular risk …

Bleeding is an important issue in cardiothoracic surgery, and about 20% of all blood
products are transfused in this clinical setting worldwide. Transfusion practices, however …

Nowadays patients receiving blood components are exposed to much less transfusion-
transmitted infectious diseases than three decades before when among others HIV was …

BACKGROUND Serious transfusion‐associated adverse events are rare in the United
States. To enhance blood safety, various measures have been developed. With use of data …

The use of pathogen reduction technologies (PRT s) for labile blood components is slowly
but steadily increasing. While pathogen‐reduced plasma is already used routinely, efficacy …

Since the late sixties, platelet concentrates are transfused to patients presenting with severe
thrombocytopenia, platelet function defects, injuries, or undergoing surgery, to prevent the …

The transfusion of platelets for both prophylaxis and treatment of bleeding is relevant to all
areas of medicine and surgery. Historically, guidance regarding platelet transfusion has …

BACKGROUND Pathogen inactivation (PI) is a new approach to blood safety that may
introduce additional costs. This study identifies costs that could be eliminated, thereby …