The Japanese Society of Hypertension (JSH) revised the Guidelines for the Management of
Hypertension 2014 (JSH 2014), and published the JSH 2019. In the development of the JSH …

Background: Intraindividual blood pressure (BP) fluctuates dynamically over time. Previous
studies suggested an adverse link between greater visit-to-visit variability in systolic blood …

Objective Previous studies have shown that visit-to-visit blood pressure variability (BPV) is
associated with chronic kidney disease (CKD). However, the results have not been …

Experimental studies conducted on animal and human endothelium suggested that higher
systolic blood pressure (SBP) variability reduces bioavailability of nitric oxide and increases …

Background A simple and readily available biomarker can provide an effective approach for
the surveillance of type 2 diabetes mellitus (T2DM) in the elderly. In this research, we aim to …

Variability is the law of life. The concept of entropy and the second law of thermodynamics
suggest that systems naturally progress from order to disorder. Conversely, most biological …

Initiation of blockade of the renin-angiotensin system may cause an acute decrease in
glomerular filtration rate (GFR): the prognostic significance of this is unknown. We did a post …

Although many studies that have examined the relationship of type and amount of food and
the frequency of eating with new onset of diabetes, there are few reports on the relationship …

Background: Recent evidence indicates that long-term visit-to-visit blood pressure variability
(BPV) may be associated with risk of cardiovascular disease. We, therefore, aimed to …

Results Over a mean follow-up of 3.5 years, 297 outcomes occurred. After multivariable
adjustment, including baseline eGFR and mean systolic BP, the hazard ratios for the …