The oxytocin receptor: from intracellular signaling to behavior
B Jurek, ID Neumann - Physiological reviews, 2018 - journals.physiology.org
The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …
Neuroscience of addiction: relevance to prevention and treatment
ND Volkow, M Boyle - American Journal of Psychiatry, 2018 - Am Psychiatric Assoc
Addiction, the most severe form of substance use disorder, is a chronic brain disorder
molded by strong biosocial factors that has devastating consequences to individuals and to …
molded by strong biosocial factors that has devastating consequences to individuals and to …
Influence of stress associated with chronic alcohol exposure on drinking
HC Becker - Neuropharmacology, 2017 - Elsevier
Stress is commonly regarded as an important trigger for relapse and a significant factor that
promotes increased motivation to drink in some individuals. However, the relationship …
promotes increased motivation to drink in some individuals. However, the relationship …
Labeled oxytocin administered via the intranasal route reaches the brain in rhesus macaques
MR Lee, TA Shnitko, SW Blue, AV Kaucher… - Nature …, 2020 - nature.com
Oxytocin may have promise as a treatment for neuropsychiatric disorders. Its therapeutic
effect may depend on its ability to enter the brain and bind to the oxytocin receptor. To date …
effect may depend on its ability to enter the brain and bind to the oxytocin receptor. To date …
Neural functions of hypothalamic oxytocin and its regulation
P Wang, SC Wang, X Liu, S Jia, X Wang, T Li… - ASN …, 2022 - journals.sagepub.com
Oxytocin (OT), a nonapeptide, has a variety of functions. Despite extensive studies on OT
over past decades, our understanding of its neural functions and their regulation remains …
over past decades, our understanding of its neural functions and their regulation remains …
Oxytocin receptors are expressed on dopamine and glutamate neurons in the mouse ventral tegmental area that project to nucleus accumbens and other mesolimbic …
J Peris, K MacFadyen, JA Smith… - Journal of …, 2017 - Wiley Online Library
The mesolimbic dopamine (DA) circuitry determines which behaviors are positively
reinforcing and therefore should be encoded in the memory to become a part of the …
reinforcing and therefore should be encoded in the memory to become a part of the …
Oxytocin reduces alcohol cue-reactivity in alcohol-dependent rats and humans
AC Hansson, A Koopmann, S Uhrig, S Bühler… - …, 2018 - nature.com
Approved pharmacological treatments for alcohol use disorder are limited in their
effectiveness, and new drugs that can easily be translated into the clinic are warranted. One …
effectiveness, and new drugs that can easily be translated into the clinic are warranted. One …
Role of oxytocin in the control of stress and food intake
T Onaka, Y Takayanagi - Journal of neuroendocrinology, 2019 - Wiley Online Library
Oxytocin neurones in the hypothalamus are activated by stressful stimuli and food intake.
The oxytocin receptor is located in various brain regions, including the sensory information …
The oxytocin receptor is located in various brain regions, including the sensory information …
Medications for alcohol use disorders: An overview
Patients who suffer from alcohol use disorders (AUDs) usually go through various socio-
behavioral and pathophysiological changes that take place in the brain and other organs …
behavioral and pathophysiological changes that take place in the brain and other organs …
Oxytocin blocks enhanced motivation for alcohol in alcohol dependence and blocks alcohol effects on GABAergic transmission in the central amygdala
Oxytocin administration has been reported to decrease consumption, withdrawal, and drug-
seeking associated with several drugs of abuse and thus represents a promising …
seeking associated with several drugs of abuse and thus represents a promising …