There is growing interest in the use of oxytocin (OT) as a potential treatment for alcohol and
other substance-use disorders. OT is a neuropeptide that modulates adaptive processes …

Drugs that act on the brain oxytocin (OXT) system may provide a much-needed treatment
breakthrough for substance-use disorders. Targeting the brain OXT system has the potential …

The neuropeptide oxytocin (OXT) plays a key role in adaptive processes associated with
reward, tolerance, memory and stress responses. Through interactions with brain reward …

Coronary artery disease (CAD) is a major cardiovascular disease responsible for high
morbidity and mortality worldwide. The major pathophysiological basis of CAD is …

Background Excessive ethanol (EtOH) consumption remains an important health concern
and effective treatments are lacking. The central oxytocin system has emerged as a …

Interest for the use of oxytocin as a treatment for addiction began over 40 years ago. Better
known for its roles in parturition, lactation and pair bonding, oxytocin also has anxiolytic …

Oxytocin (OT) and vasopressin (AVP) are endogenous ligands for OT and AVP receptors in
the brain and in the peripheral system. Several studies demonstrate that OT and AVP have …

Early life adversity can set the trajectory for later psychiatric disorders, including substance
use disorders. There are a host of neurobiological factors that may play a role in the …

The neuropeptide oxytocin has emerged as a promising pharmacotherapy for
methamphetamine (METH) addiction, and clinical trials of intranasal oxytocin are underway …

Rationale The neuropeptide oxytocin (OXT) has emerged as a potential therapeutic
intervention in the treatment of both alcohol use disorder (AUD) and stress-related …