The effect of chronic oxytocin treatment during abstinence from methamphetamine self-administration on incubation of craving, reinstatement, and anxiety

NA Everett, SJ Baracz, JL Cornish - Neuropsychopharmacology, 2020 - nature.com
Methamphetamine (METH) abuse is characterised by chronic relapse and anxiety, for which
there are no effective pharmacotherapies. Acute treatment with the neuropeptide oxytocin …

Role of oxytocin in the ventral tegmental area in social reinforcement

JM Borland, KN Grantham, LM Aiani, KJ Frantz… - …, 2018 - Elsevier
The rewarding properties of social interactions play a critical role in the development and
maintenance of social relationships, and deficits in social reward are associated with various …

Oxytocin signaling in the treatment of drug addiction: Therapeutic opportunities and challenges

X Che, J Cai, Y Liu, T Xu, J Yang, C Wu - Pharmacology & therapeutics, 2021 - Elsevier
Drug addiction is one of the leading causes of mortality worldwide. Despite great advances
were achieved in understanding the neurobiology of drug addiction, the therapeutic options …

Role of oxytocin and vasopressin in neuropsychiatric disorders: therapeutic potential of agonists and antagonists

V Cid-Jofré, M Moreno, M Reyes-Parada… - International Journal of …, 2021 - mdpi.com
Oxytocin (OT) and vasopressin (AVP) are hypothalamic neuropeptides classically
associated with their regulatory role in reproduction, water homeostasis, and social …

[图书][B] Alcohol: Neurobiology of Addiction

GF Koob, MA Arends, ML McCracken, M Le Moal - 2021 - books.google.com
A current survey and synthesis of the most important findings in our understanding of the
neurobiological mechanisms of addiction is detailed in our Neurobiology of Addiction series …

Social modulation of drug use and drug addiction

Y Pelloux, E Giorla, C Montanari, C Baunez - Neuropharmacology, 2019 - Elsevier
This review aims to demonstrate how social science and behavioral neurosciences have
highlighted the influence of social interactions on drug use in animal models. In …

Factors contributing to the escalation of alcohol consumption

MT Bowen, O George, DE Muskiewicz… - … & Biobehavioral Reviews, 2022 - Elsevier
Understanding factors that contribute to the escalation of alcohol consumption is key to
understanding how an individual transitions from non/social drinking to AUD and to …

Oxytocin, tolerance, and the dark side of addiction

CA Pedersen - International review of neurobiology, 2017 - Elsevier
Substance use disorders blight the lives of millions of people and inflict a heavy financial
burden on society. There is a compelling need for new pharmacological treatments as …

Oxytocin reverses ethanol consumption and neuroinflammation induced by social defeat in male mice

MD Reguilón, C Ferrer-Pérez, J Miñarro… - Hormones and …, 2021 - Elsevier
Oxytocin (OXT) modulates social interactions, attenuates stressful responses and can
decrease drug-seeking and taking behaviors. In previous studies, we observed that social …

Oxytocin reduces alcohol consumption in prairie voles

JR Stevenson, SM Wenner, DM Freestone… - Physiology & …, 2017 - Elsevier
Alcohol use disorder (AUD) negatively affects millions of people every year in the United
States, and effective treatments for AUD are still needed. The neuropeptide oxytocin has …