A pronounced decrease of oxytocin and increase of oxytocin receptor binding sites were
recently reported in male alcohol dependent rats and male alcohol dependent patients …

Alcohol use disorder has multiple characteristics including excessive ethanol consumption,
impaired control over drinking behaviors, craving and withdrawal symptoms, compulsive …

The neuropeptide oxytocin has shown promise as an effective therapy in pre-clinical models
of methamphetamine (METH) addiction. The nucleus accumbens core (NAcc) has been …

Drug abuse is a worldwide problem that leads to negative physical, mental, and economic
consequences. Although pharmacological strategies for drug addiction management have …

Recently, oxytocin (OXT) has been investigated for its potential therapeutic role in addiction.
OXT has been found to diminish various drug-seeking and drug-induced behaviors …

Interoception, ie the perception and appraisal of internal bodily signals, is related to the
phenomenon of craving, and is reportedly disrupted in alcohol use disorders. The hormone …

Background: The incentive sensitisation theory of addiction posits that drug-associated
stimuli become imbued with incentive motivational properties, driving pathological drug …

Background There is high comorbidity of posttraumatic stress disorder (PTSD) and alcohol
use disorder with few effective treatment options. Animal models of PTSD have shown …

The mesolimbic dopamine system is the primary neural circuit mediating motivation,
reinforcement, and reward-related behavior. The activity of this system and multiple …

Oxytocin potently reduces food intake and is a potential target system for obesity treatment.
A better understanding of the behavioral and neurobiological mechanisms mediating …