Updates to the modern diagnosis of GERD: Lyon consensus 2.0

CP Gyawali, R Yadlapati, R Fass, D Katzka… - Gut, 2024 - gut.bmj.com
The Lyon Consensus provides conclusive criteria for and against the diagnosis of gastro-
oesophageal reflux disease (GERD), and adjunctive metrics that consolidate or refute GERD …

The risks of long-term use of proton pump inhibitors: a critical review

M Jaynes, AB Kumar - Therapeutic advances in drug safety, 2019 - journals.sagepub.com
Proton pump inhibitors (PPIs) are among the most frequently prescribed medications. Their
use is likely even higher than estimated due to an increase in the number of PPIs available …

Effective and safe proton pump inhibitor therapy in acid-related diseases–a position paper addressing benefits and potential harms of acid suppression

C Scarpignato, L Gatta, A Zullo, C Blandizzi… - BMC medicine, 2016 - Springer
Background The introduction of proton pump inhibitors (PPIs) into clinical practice has
revolutionized the management of acid-related diseases. Studies in primary care and …

Proton pump inhibitors for functional dyspepsia

MI Pinto‐Sanchez, Y Yuan, P Bercik… - Cochrane Database …, 2017 - cochranelibrary.com
Background Functional dyspepsia (FD or non‐ulcer dyspepsia) is defined as continuous or
frequently recurring epigastric pain or discomfort for which no organic cause can be found …

[HTML][HTML] Effect of concomitant medications with immune-modulatory properties on the outcomes of patients with advanced cancer treated with immune checkpoint …

S Buti, M Bersanelli, F Perrone, M Tiseo, M Tucci… - European Journal of …, 2021 - Elsevier
Background Concomitant medications are known to impact on clinical outcomes of patients
treated with immune checkpoint inhibitors (ICIs). We aimed weighing the role of different …

Proton pump inhibitors: use and misuse in the clinical setting

V Savarino, E Marabotto, P Zentilin… - Expert review of …, 2018 - Taylor & Francis
Introduction: The introduction of proton pump inhibitors (PPIs) into clinical practice has
greatly improved our therapeutic approach to acid-related diseases for their efficacy and …

Peptic ulcer disease

E Sverdén, L Agréus, JM Dunn, J Lagergren - Bmj, 2019 - bmj.com
Peptic ulcer disease presents with gastrointestinal symptoms similar to dyspepsia and can
be difficult to distinguish clinically. It can have potentially serious complications such as …

Proton pump inhibitors and fracture risk: a review of current evidence and mechanisms involved

BKS Thong, S Ima-Nirwana, KY Chin - International journal of …, 2019 - mdpi.com
The number of patients with gastroesophageal problems taking proton pump inhibitors
(PPIs) is increasing. Several studies suggested a possible association between PPIs and …

Association between proton pump inhibitor use and risk of progression of chronic kidney disease

DCF Klatte, A Gasparini, H Xu, P de Deco, M Trevisan… - Gastroenterology, 2017 - Elsevier
Background & Aims Proton pump inhibitors (PPI) have been associated with acute kidney
injury and recent studies suggest that they may be associated with the risk of chronic kidney …

Use of proton pump inhibitors in adults in France: a nationwide drug utilization study

M Lassalle, T Le Tri, M Bardou, M Biour… - European journal of …, 2020 - Springer
Purpose Proton pump inhibitor (PPI) drugs are approved for the management of gastric acid–
related diseases, mainly treatment of gastroesophageal reflux disease, treatment of …