[HTML][HTML] Impaired TFEB-mediated autophagy-lysosome fusion promotes tubular cell cycle G2/M arrest and renal fibrosis by suppressing ATP6V0C expression and …

X Ren, J Wang, H Wei, X Li, Y Tian… - … Journal of Biological …, 2024 - ncbi.nlm.nih.gov
Increasing evidence suggests that autophagy plays a major role during renal fibrosis.
Transcription factor EB (TFEB) is a critical regulator of autophagy-and lysosome-related …

TXNIP deficiency attenuates renal fibrosis by modulating mTORC1/TFEB-mediated autophagy in diabetic kidney disease

Y Du, M Wu, S Song, Y Bian, Y Shi - Renal Failure, 2024 - Taylor & Francis
Thioredoxin-interacting protein (TXNIP) is an important regulatory protein for thioredoxin
(TRX) that elicits the generation of reactive oxygen species (ROS) by inhibiting the redox …

[PDF][PDF] Effect of Synthetic CaM and NFAT Oligodeoxynucleotide on MPP+-Stimulated Mesencephalic Neurons

J Park, KM Jang - Journal of Interdisciplinary Genomics, 2023 - koreascience.kr
Background: Ca2+ signaling plays a vital role in neuronal signaling and altered Ca2+
homeostasis in Parkinson's disease (PD). Overexpression of αSYN significantly promote the …