Exposure to pollutants altered glucocorticoid signaling and clock gene expression in female mice. Evidence of tissue-and sex-specificity

N Vega, C Pinteur, G Buffelan, E Loizon, H Vidal… - Chemosphere, 2021 - Elsevier
Environmental pollutants suspected of disrupting the endocrine system are considered
etiologic factors in the epidemic of metabolic disorders. As regulation of energy metabolism …

Persistent organic pollutants and hyperuricemia in the US general population

YM Lee, SG Bae, SH Lee, DR Jacobs Jr, DH Lee - Atherosclerosis, 2013 - Elsevier
Background Background exposure to persistent organic pollutants (POPs) has emerged as
a new risk factor for metabolic syndrome (MetS), while hyperuricemia is associated with …

Mobilization of environmental toxicants following bariatric surgery

RH Brown, DK Ng, K Steele, M Schweitzer… - …, 2019 - Wiley Online Library
Objective Persistent organic pollutants (POPs) are lipophilic environmental toxicants that
accumulate in adipose tissue. Weight loss leads to mobilization and increased redistribution …

[HTML][HTML] Markers of acute toxicity of DDT exposure in pancreatic beta-cells determined by a proteomic approach

N Pavlikova, J Sramek, M Jelinek, P Halada, J Kovar - PLoS One, 2020 - journals.plos.org
Many compounds have the potential to harm pancreatic beta-cells; organochlorine
pollutants belong to those compounds. In this work, we aimed to find markers of acute …

[HTML][HTML] Upregulation of vitamin D-binding protein is associated with changes in insulin production in pancreatic beta-cells exposed to p,p′-DDT and p,p′-DDE

N Pavlíková, P Daniel, J Šrámek, M Jelínek… - Scientific Reports, 2019 - nature.com
Persistent organochlorine pollutants (POPs) gradually accumulate in the human organism
due to their presence in the environment. Some studies have described a correlation …

Exposure to low doses of dechlorane plus promotes adipose tissue dysfunction and glucose intolerance in male mice

V Peshdary, G Styles, M Rigden, D Caldwell… - …, 2020 - academic.oup.com
The prevalence of type 2 diabetes (T2D) continues to increase worldwide. It is well
established that genetic susceptibility, obesity, overnutrition and a sedentary life style are …

Metabolic disruption in context: Clinical avenues for synergistic perturbations in energy homeostasis by endocrine disrupting chemicals

RM Sargis - Endocrine Disruptors, 2015 - Taylor & Francis
The global epidemic of metabolic disease is a clear and present danger to both individual
and societal health. Understanding the myriad factors contributing to obesity and diabetes is …

Organochlorine pesticides and polychlorinated biphenyls (PCBs) in early adulthood and blood lipids over a 23-year follow-up

JR Suarez-Lopez, CG Clemesha, M Porta… - Environmental …, 2019 - Elsevier
Background Some evidence in humans suggests that persistent organic pollutants (POPs),
including organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs), may …

Lipophilic chemical exposure as a cause of type 2 diabetes (T2D)

HI Zeliger - Reviews on environmental health, 2013 - degruyter.com
The prevalence of type 2 diabetes (T2D) is increasing worldwide in pandemic-like numbers.
It is considered, at least in part, to be an environmental illness. Recent research has shown …

Persistent organic pollutants and concern over the link with insulin resistance related metabolic diseases

S Mostafalou - Reviews of Environmental Contamination and …, 2016 - Springer
Persistent organic pollutants (POPs) are mostly halogenated compounds tending to persist
in the environment, enter into the food chain, and accumulate in fat mass of mammals due to …