Ethinyl estradiol and 17β-estradiol in combined oral contraceptives: pharmacokinetics, pharmacodynamics and risk assessment

FZ Stanczyk, DF Archer, BR Bhavnani - Contraception, 2013 - Elsevier
The need to seek improved combined oral contraceptive (COC) efficacy, with fewer health
risks and better acceptability, has been ongoing since the introduction of COCs more than …

Hypertension in women

T Rosenthal, S Oparil - Journal of human hypertension, 2000 - nature.com
Hypertension in women has received less attention than hypertension in men, and the major
controlled trials of antihypertensive therapy have been carried out in populations made up …

Effects of oral contraceptives on glucose flux and substrate oxidation rates during rest and exercise

SH Suh, GA Casazza, MA Horning… - Journal of applied …, 2003 - journals.physiology.org
We examined the effects of oral contraceptives (OC) on glucose flux and whole body
substrate oxidation rates during rest (90 min) and two exercise intensities [60-min leg …

A prospective study of oral contraceptives and NIDDM among US women

L Chasan-Taber, WC Willett, MJ Stampfer… - Diabetes …, 1997 - Am Diabetes Assoc
OBJECTIVE To examine prospectively the association between modern oral contraceptives
with low doses of estrogen and progestin and subsequent incidence of NIDDM. RESEARCH …

Oral contraceptive use and the risk of type 2 (non-insulin-dependent) diabetes mellitus in a large prospective study of women

EB Rimm, JE Manson, MJ Stampfer, GA Colditz… - Diabetologia, 1992 - Springer
We examined the association between oral contraceptive use and incidence of Type 2 (non-
insulin-dependent) diabetes mellitus among 115117 female nurses free of diabetes …

The effect of a desogestrel-containing oral contraceptive on glucose tolerance and leptin concentrations in hyperandrogenic women

S Nader, MG Riad-Gabriel… - The Journal of Clinical …, 1997 - academic.oup.com
Ovarian hyperandrogenism can be associated with insulin resistance, hyperinsulinemia,
glucose intolerance, and obesity. High levels of the lipostatic hormone, leptin, have also …

RAS and sex differences in diabetic nephropathy

S Clotet, M Riera, J Pascual… - American Journal of …, 2016 - journals.physiology.org
The incidence and progression of kidney diseases are influenced by sex. The renin-
angiotensin system (RAS) is an important regulator of cardiovascular and renal function. Sex …

Common onion (Allium cepa) extract reverses cadmium-induced organ toxicity and dyslipidaemia via redox alteration in rats

SF Ige, RE Akhigbe - Pathophysiology, 2013 - Elsevier
Abstract Background: Cadmium (Cd) remains an important environmental pollutant of public
health concern as it causes organ toxicity, and cardiovascular diseases (CVD), but the roles …

Cardiovascular disease: pathogenesis, epidemiology, and risk among users of oral contraceptives who smoke

WP Castelli - American journal of obstetrics and gynecology, 1999 - Elsevier
Smoking increases the risk of lung cancer and cardiovascular disease among persons of
both sexes. The risk of cardiovascular disease is further increased among users of oral …

Use of cyproterone acetate/ethinylestradiol in polycystic ovary syndrome: rationale and practical aspects

X Ruan, A Kubba, A Aguilar… - The European Journal of …, 2017 - Taylor & Francis
Introduction: Polycystic ovary syndrome (PCOS) is a common, heterogeneous disorder
characterised by hyperandrogenic skin symptoms, irregular menstruation and subfertility …