[HTML][HTML] Dissecting the effects of androgen deprivation therapy on cadherin switching in advanced prostate cancer: A molecular perspective

L Varisli, V Tolan, JH Cen, S Vlahopoulos… - Oncology …, 2022 - ncbi.nlm.nih.gov
Prostate cancer is one of the most often diagnosed malignancies in males and its
prevalence is rising in both developed and developing countries. Androgen deprivation …

[HTML][HTML] Cancer invasion and metastasis: Insights from murine pubertal mammary gland morphogenesis

JM Githaka, L Pirayeshfard, S Goping - Biochimica et Biophysica Acta (BBA …, 2023 - Elsevier
Cancer invasion and metastasis accounts for the majority of cancer related mortality. A better
understanding of the players that drive the aberrant invasion and migration of tumors cells …

[HTML][HTML] Therapy-resistant breast cancer in focus: Clinically relevant mitigation by flavonoids targeting cancer stem cells

A Mazurakova, L Koklesova, D Vybohova… - Frontiers in …, 2023 - frontiersin.org
Significant limitations of the reactive medical approach in breast cancer management are
clearly reflected by alarming statistics recorded worldwide. According to the WHO updates …

CRIPTO Is a marker of chemotherapy-induced stem cell expansion in non-small cell lung cancer

F Francescangeli, ML De Angelis, R Rossi… - Frontiers in …, 2022 - frontiersin.org
Chemotherapy is the mainstay for the treatment of non-small cell lung cancer (NSCLC).
However, NSCLC cells are either intrinsically chemoresistant or rapidly develop therapy …

Antibody-Drug Conjugates as a Novel Therapeutic Modality to Treat Recurrent Refractory Germ Cell Tumors.

N Udvorková, A Fekiačová… - … of Physiology-Cell …, 2024 - journals.physiology.org
This review provides a rationale for using the Food and Drug Administration (FDA)-approved
antibody-drug conjugates (ADCs) for implementing as therapy in recurrent refractory germ …

Recombinant humanized Fab fragments targeting the CFC domain of human Cripto-1

A Sandomenico, F Selis, JP Sivaccumar… - Biochemical and …, 2024 - Elsevier
In the era of immunotherapy, the targeting of disease-specific biomarkers goes hand in hand
with the development of highly selective antibody-based reagents having optimal …

Effect of combination of radiotherapy and docetaxel on Cripto-1, β-catenin and DBC1 expression in breast cancer patients

T Zang - Indian Journal of Experimental Biology (IJEB), 2024 - or.niscpr.res.in
Among all cancer types, blood cancer tops in total number of estimated cases and ranks
fourth in fatalities caused by cancer. Early diagnosis and treatment, particularly for breast …

Liver receptor homolog 1 (LRH-1) regulates follicle vasculature during ovulation in mice

A Guzmán, CHK Hughes, BD Murphy - Reproduction, 2022 - rep.bioscientifica.com
In brief It is well-established that liver receptor homolog 1 (LRH-1/NR5A2) regulates the
ovarian function and is required for ovulation and luteinization in mice. In the present …

[HTML][HTML] Methyl vanillate for inhibiting the proliferation, migration, and epithelial-mesenchymal transition of ovarian cancer cells via the ZEB2/Snail signaling pathway

L Wang, Y Miao, J Wen, J Cheng, Q Wen… - Translational Cancer …, 2023 - ncbi.nlm.nih.gov
Background Globally, ovarian cancer is the leading cause of female reproductive-related
death, with a 5-year survival rate below 50%. Conventional therapies, such as cancer cell …

The splicing switch of SLK controls tumor progression partially via different associations with occludin

YQ Yang, SR Zhang, Y Hu, JF Li, JW Guan, WJ Zhang… - bioRxiv, 2022 - biorxiv.org
Aberrant RNA splicing is significantly associated with tumorigenesis and cancer
progression. From a pan-cancer transcriptome analysis, we discovered a critical cancer …