Mechanisms of cell size regulation in slow-growing Escherichia coli cells: discriminating models beyond the adder

C Nieto, CA Vargas-García, JM Pedraza… - npj Systems Biology and …, 2024 - nature.com
Under ideal conditions, Escherichia coli cells divide after adding a fixed cell size, a strategy
known as the adder. This concept applies to various microbes and is often explained as the …

[HTML][HTML] Coupling cell size regulation and proliferation dynamics of C. glutamicum reveals cell division based on surface area

C Nieto, S Täuber, L Blöbaum, Z Vahdat, A Grünberger… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Single cells actively coordinate growth and division to regulate their size, yet how this size
homeostasis at the single-cell level propagates over multiple generations to impact clonal …

[PDF][PDF] Statistical properties of dynamical models underlying cell size homeostasis

C Nieto, CA Vargas-Garcia, A Singh - tech. rep., Center for Open Science, 2023 - osf.io
In this contribution, we use the framework of discrete-event dynamical systems to model a
fundamental aspect of lifethe proliferation of cells. This process starts with a newborn cell …