Consensus paper of the WFSBP task force on cannabis, cannabinoids and psychosis

DC D'Souza, M DiForti, S Ganesh… - The World Journal of …, 2022 - Taylor & Francis
Objectives The liberalisation of cannabis laws, the increasing availability and potency of
cannabis has renewed concern about the risk of psychosis with cannabis. Methods The …

Cannabis and psychosis

ML West, S Sharif - Psychiatric Clinics, 2023 - psych.theclinics.com
Psychosis is a cluster of symptoms that involve difficulties knowing what is real and what is
not real. As with any mental health experience, psychosis can be seen as a spectrum of …

The thalamus in psychosis spectrum disorder

A Anticevic, MM Halassa - Frontiers in Neuroscience, 2023 - frontiersin.org
Psychosis spectrum disorder (PSD) affects 1% of the world population and results in a
lifetime of chronic disability, causing devastating personal and economic consequences …

Investigating the “two-hit hypothesis”: effects of prenatal maternal immune activation and adolescent cannabis use on neurodevelopment in mice

E Guma, L Cupo, W Ma, D Gallino, L Moquin… - Progress in Neuro …, 2023 - Elsevier
Prenatal exposure to maternal immune activation (MIA) and chronic adolescent cannabis
use are both risk factors for neuropsychiatric disorders. However, exposure to a single risk …

Prenatal risk factors and postnatal cannabis exposure: assessing dual models of schizophrenia-like rodents

C Martín-Cuevas, VD Ramos-Herrero… - Neuroscience & …, 2023 - Elsevier
Schizophrenia (SCZ) is a multifactorial neurodevelopmental disorder caused by genetic and
environmental alterations, especially during prenatal stages. On the other hand, cannabis …

Chronic exposure to a synthetic cannabinoid alters cerebral brain metabolism and causes long-lasting behavioral deficits in adult mice

C Bouter, FW Ott, D Günther, L Weig… - Journal of Neural …, 2023 - Springer
In recent years, there has been growing evidence that cannabinoids have promising
medicinal and pharmacological effects. However, the growing interest in medical cannabis …

Cannabinoid CB2 receptors and hypersensitivity to methamphetamine: Vulnerability to schizophrenia

A Canseco-Alba, K Tabata, Y Momoki… - Progress in Neuro …, 2024 - Elsevier
The human cannabinoid receptor 2 (CB2R) gene CNR2 has been associated with
schizophrenia development. Inbred mice treated with the CB2R inverse agonist AM630 and …

Marijuana use in children: An update focusing on pediatric tetrahydrocannabinol and cannabidiol use

MJ Stoner, A Dietrich, SHF Lam, JJ Wall… - Journal of the …, 2022 - Wiley Online Library
Cannabis is the most used recreational drug in the United States, and its use is increasing
among children and adolescents. With the increase in legalized use, there have been …

Impact of cannabis use on brain metabolism using 31P and 1H magnetic resonance spectroscopy

M Fenzl, M Backens, S Bodea, M Wittemann, F Werler… - Neuroradiology, 2023 - Springer
Purpose This prospective cross-sectional study investigated the influence of regular
cannabis use on brain metabolism in young cannabis users by using combined proton and …

Cannabis, neurodevelopment, and the “two-hit” hypothesis

E Guma, L Cupo, MM Chakravarty - Cannabis Use, Neurobiology …, 2023 - Elsevier
Previous epidemiological research has drawn attention to a potential association between
exposure to cannabis and the emergence of psychotic disorders, such as schizophrenia; …