Bioprinting for vascular and vascularized tissue biofabrication
Bioprinting is a promising technology to fabricate design-specific tissue constructs due to its
ability to create complex, heterocellular structures with anatomical precision. Bioprinting …
ability to create complex, heterocellular structures with anatomical precision. Bioprinting …
[PDF][PDF] Stem cell therapies for treating diabetes: progress and remaining challenges
Restoration of insulin independence and normoglycemia has been the overarching goal in
diabetes research and therapy. While whole-organ and islet transplantation have become …
diabetes research and therapy. While whole-organ and islet transplantation have become …
Single-cell analysis of the cellular heterogeneity and interactions in the injured mouse spinal cord
LM Milich, JS Choi, C Ryan, SR Cerqueira… - Journal of Experimental …, 2021 - rupress.org
The wound healing process that occurs after spinal cord injury is critical for maintaining
tissue homeostasis and limiting tissue damage, but eventually results in a scar-like …
tissue homeostasis and limiting tissue damage, but eventually results in a scar-like …
[HTML][HTML] Neurocristopathies: New insights 150 years after the neural crest discovery
The neural crest (NC) is a transient, multipotent and migratory cell population that generates
an astonishingly diverse array of cell types during vertebrate development. These cells …
an astonishingly diverse array of cell types during vertebrate development. These cells …
Cellular and molecular mechanisms coordinating pancreas development
The pancreas is an endoderm-derived glandular organ that participates in the regulation of
systemic glucose metabolism and food digestion through the function of its endocrine and …
systemic glucose metabolism and food digestion through the function of its endocrine and …
The human islet: mini-organ with mega-impact
JT Walker, DC Saunders, M Brissova… - Endocrine …, 2021 - academic.oup.com
This review focuses on the human pancreatic islet—including its structure, cell composition,
development, function, and dysfunction. After providing a historical timeline of key …
development, function, and dysfunction. After providing a historical timeline of key …
Signals in the pancreatic islet microenvironment influence β‐cell proliferation
KI Aamodt, AC Powers - Diabetes, Obesity and Metabolism, 2017 - Wiley Online Library
The progressive loss of pancreatic β‐cell mass that occurs in both type 1 and type 2
diabetes is a primary factor driving efforts to identify strategies for effectively increasing …
diabetes is a primary factor driving efforts to identify strategies for effectively increasing …
[PDF][PDF] Islet microenvironment, modulated by vascular endothelial growth factor-A signaling, promotes β cell regeneration
M Brissova, K Aamodt, P Brahmachary, N Prasad… - Cell metabolism, 2014 - cell.com
Pancreatic islet endocrine cell and endothelial cell (EC) interactions mediated by vascular
endothelial growth factor-A (VEGF-A) signaling are important for islet differentiation and the …
endothelial growth factor-A (VEGF-A) signaling are important for islet differentiation and the …
The molecular and morphogenetic basis of pancreas organogenesis
HL Larsen, A Grapin-Botton - Seminars in cell & developmental biology, 2017 - Elsevier
The pancreas is an essential endoderm-derived organ that ensures nutrient metabolism via
its endocrine and exocrine functions. Here we review the essential processes governing the …
its endocrine and exocrine functions. Here we review the essential processes governing the …
Biology of bone: the vasculature of the skeletal system
EC Watson, RH Adams - Cold Spring …, 2018 - perspectivesinmedicine.cshlp.org
Blood vessels are essential for the distribution of oxygen, nutrients, and immune cells, as
well as the removal of waste products. In addition to this conventional role as a versatile …
well as the removal of waste products. In addition to this conventional role as a versatile …