Asthma is a chronic inflammation of lower airway disease, characterized by bronchial
hyperresponsiveness. Type I hypersensitivity underlies all atopic diseases including allergic …

Abstract The serotonin 7 (5-HT7) receptor was the last serotonin receptor subtype to be
discovered in 1993. This receptor system has been implicated in several central nervous …

Asthma is an inflammatory disease of the lung characterized by airways hyper-
responsiveness (AHR), inflammation, and mucus hyperproduction. Current mainstream …

Aims Although the bulk of research into the biology of serotonin 5-HT 2A receptors has
focused on its role in the CNS, selective activation of these receptors in peripheral tissues …

This study aimed to investigate the effects of the 5-HT7 receptor agonist (LP44) and
antagonist (SB269970) on LPS-induced in vivo tissue damage and cell culture by molecular …

Sepsis is a complex pathophysiological event involving metabolic acidosis, systemic
inflammatory response syndrome, tissue damage and multiple organ dysfunction syndrome …

The aim of this study was:(1) to investigate possible role for 5-HT 7 receptors in carrageenan
induced inflammatory paw oedema in rats;(2) to determine the presence of 5-HT 7 receptors …

Ozone, a pervasive environmental pollutant, adversely affects functional lung growth in
children. Animal studies demonstrate that altered lung development is associated with …

Introduction Because only a small portion of NSCLC (non-small-cell lung cancer) patients
benefit from molecular targeted therapy or immunotherapy and do not develop therapeutic …

We have investigated the effects of slow (GYY4137) and rapid (NaHS) hydrogen sulfide (H 2
S) releasing donors in lipopolysaccharide (LPS)-induced airway inflammation in mice. LPS …