p53 in ferroptosis regulation: the new weapon for the old guardian
Although the conventional activities of p53 such as cell cycle arrest, senescence, and
apoptosis are well accepted as the major checkpoints in stress responses, accumulating …
apoptosis are well accepted as the major checkpoints in stress responses, accumulating …
Ferroptosis: machinery and regulation
Ferroptosis is an iron-dependent, non-apoptotic form of regulated cell death caused by lipid
peroxidation, which is controlled by integrated oxidation and antioxidant systems. The iron …
peroxidation, which is controlled by integrated oxidation and antioxidant systems. The iron …
LncRNA‐mediated posttranslational modifications and reprogramming of energy metabolism in cancer
YT Tan, JF Lin, T Li, JJ Li, RH Xu… - Cancer …, 2021 - Wiley Online Library
Altered metabolism is a hallmark of cancer, and the reprogramming of energy metabolism
has historically been considered a general phenomenon of tumors. It is well recognized that …
has historically been considered a general phenomenon of tumors. It is well recognized that …
Long noncoding RNA NEAT1 promotes ferroptosis by modulating the miR-362-3p/MIOX axis as a ceRNA
Y Zhang, M Luo, X Cui, D O'Connell… - Cell Death & …, 2022 - nature.com
Ferroptosis, a novel form of regulated cell death induced by iron-dependent lipid
peroxidation, plays an essential role in the development and drug resistance of tumors …
peroxidation, plays an essential role in the development and drug resistance of tumors …
New insights into the interplay between long non‐coding RNAs and RNA‐binding proteins in cancer
ZT Yao, YM Yang, MM Sun, Y He, L Liao… - Cancer …, 2022 - Wiley Online Library
With the development of proteomics and epigenetics, a large number of RNA‐binding
proteins (RBPs) have been discovered in recent years, and the interaction between long …
proteins (RBPs) have been discovered in recent years, and the interaction between long …
Ferroptosis is a type of autophagy-dependent cell death
Macroautophagy (hereafter referred to as autophagy) involves an intracellular degradation
and recycling system that, in a context-dependent manner, can either promote cell survival …
and recycling system that, in a context-dependent manner, can either promote cell survival …
Ferroptosis and cancer: mitochondria meet the “iron maiden” cell death
Ferroptosis is a new type of oxidative regulated cell death (RCD) driven by iron-dependent
lipid peroxidation. As major sites of iron utilization and master regulators of oxidative …
lipid peroxidation. As major sites of iron utilization and master regulators of oxidative …
Emerging mechanisms and targeted therapy of ferroptosis in cancer
H Wang, Y Cheng, C Mao, S Liu, D Xiao, J Huang… - Molecular Therapy, 2021 - cell.com
Ferroptosis is an iron-and lipid reactive oxygen species (ROS)-dependent form of
programmed cell death that is distinct from other forms of regulatory cell death at the …
programmed cell death that is distinct from other forms of regulatory cell death at the …
The application of ferroptosis in diseases
Ferroptosis is a new kind of regulated cell death that is characterized by highly iron-
dependent lipid peroxidation. Ferroptosis involves various biology processes, such as iron …
dependent lipid peroxidation. Ferroptosis involves various biology processes, such as iron …
LncRNA HEPFAL accelerates ferroptosis in hepatocellular carcinoma by regulating SLC7A11 ubiquitination
B Zhang, W Bao, S Zhang, B Chen, X Zhou… - Cell death & …, 2022 - nature.com
Ferroptosis is a new type of cell death that has been recognized in recent years and is
different from apoptosis, autophagy, and necrosis. It is mainly due to cellular iron …
different from apoptosis, autophagy, and necrosis. It is mainly due to cellular iron …