p53 in ferroptosis regulation: the new weapon for the old guardian

Y Liu, W Gu - Cell Death & Differentiation, 2022 - nature.com
Although the conventional activities of p53 such as cell cycle arrest, senescence, and
apoptosis are well accepted as the major checkpoints in stress responses, accumulating …

Ferroptosis: machinery and regulation

X Chen, J Li, R Kang, DJ Klionsky, D Tang - Autophagy, 2021 - Taylor & Francis
Ferroptosis is an iron-dependent, non-apoptotic form of regulated cell death caused by lipid
peroxidation, which is controlled by integrated oxidation and antioxidant systems. The iron …

LncRNA‐mediated posttranslational modifications and reprogramming of energy metabolism in cancer

YT Tan, JF Lin, T Li, JJ Li, RH Xu… - Cancer …, 2021 - Wiley Online Library
Altered metabolism is a hallmark of cancer, and the reprogramming of energy metabolism
has historically been considered a general phenomenon of tumors. It is well recognized that …

Long noncoding RNA NEAT1 promotes ferroptosis by modulating the miR-362-3p/MIOX axis as a ceRNA

Y Zhang, M Luo, X Cui, D O'Connell… - Cell Death & …, 2022 - nature.com
Ferroptosis, a novel form of regulated cell death induced by iron-dependent lipid
peroxidation, plays an essential role in the development and drug resistance of tumors …

New insights into the interplay between long non‐coding RNAs and RNA‐binding proteins in cancer

ZT Yao, YM Yang, MM Sun, Y He, L Liao… - Cancer …, 2022 - Wiley Online Library
With the development of proteomics and epigenetics, a large number of RNA‐binding
proteins (RBPs) have been discovered in recent years, and the interaction between long …

Ferroptosis is a type of autophagy-dependent cell death

B Zhou, J Liu, R Kang, DJ Klionsky, G Kroemer… - Seminars in cancer …, 2020 - Elsevier
Macroautophagy (hereafter referred to as autophagy) involves an intracellular degradation
and recycling system that, in a context-dependent manner, can either promote cell survival …

Ferroptosis and cancer: mitochondria meet the “iron maiden” cell death

AM Battaglia, R Chirillo, I Aversa, A Sacco, F Costanzo… - Cells, 2020 - mdpi.com
Ferroptosis is a new type of oxidative regulated cell death (RCD) driven by iron-dependent
lipid peroxidation. As major sites of iron utilization and master regulators of oxidative …

Emerging mechanisms and targeted therapy of ferroptosis in cancer

H Wang, Y Cheng, C Mao, S Liu, D Xiao, J Huang… - Molecular Therapy, 2021 - cell.com
Ferroptosis is an iron-and lipid reactive oxygen species (ROS)-dependent form of
programmed cell death that is distinct from other forms of regulatory cell death at the …

The application of ferroptosis in diseases

Y Qiu, Y Cao, W Cao, Y Jia, N Lu - Pharmacological Research, 2020 - Elsevier
Ferroptosis is a new kind of regulated cell death that is characterized by highly iron-
dependent lipid peroxidation. Ferroptosis involves various biology processes, such as iron …

LncRNA HEPFAL accelerates ferroptosis in hepatocellular carcinoma by regulating SLC7A11 ubiquitination

B Zhang, W Bao, S Zhang, B Chen, X Zhou… - Cell death & …, 2022 - nature.com
Ferroptosis is a new type of cell death that has been recognized in recent years and is
different from apoptosis, autophagy, and necrosis. It is mainly due to cellular iron …