Pulmonary fibrosis represents the end stage of a number of heterogeneous conditions and
is, to a greater or lesser degree, the hallmark of the interstitial lung diseases. It is …

The histopathologic pattern provides the most important prognostic marker for idiopathic
interstitial pneumonia; however, studies have suggested that short-term changes in lung …

Background The prognostic value of BAL fluid cell count differential in patients with
idiopathic pulmonary fibrosis (IPF) is unknown. We hypothesized that baseline BAL fluid cell …

Rationale: Exploration of FVC as it relates to mortality in idiopathic pulmonary fibrosis (IPF),
a chronic, progressive, and ultimately fatal parenchymal lung disease, is important both …

1. INTRODUCTION 1.1 An overview of the ILD guideline Since the publication of the first
BTS guidelines for diffuse lung disease nearly 10years ago, 1 the specialty has seen …

Background: In the past two decades, many advances have been made to our
understanding of interstitial lung disease (ILD) and the way we approach its treatment …

The lungs are a major site of entry of pathogens into the body and thus require rapid and
effective innate responses to prevent pathogens establishing infection and to limit their …

Background Idiopathic pulmonary fibrosis (IPF) is characterized by the insidious onset of
dyspnea or cough. However, a subset of patients has a short duration of symptoms with …

Definitive evidence of clinical efficacy in a Phase 3 trial is best shown by a beneficial impact
on a clinically meaningful endpoint—that is, an endpoint that directly measures how a …

Idiopathic pulmonary fibrosis (IPF) occurs predominantly in middle-aged and older adults
and accounts for 20% to 30% of interstitial lung diseases. It is usually progressive, resulting …