[HTML][HTML] Glycoproteomics
Protein glycosylation involves the co-translational or post-translational addition of glycans to
proteins and is a crucial protein modification in health and disease. The aim of …
proteins and is a crucial protein modification in health and disease. The aim of …
[HTML][HTML] Proteogenomic data and resources for pan-cancer analysis
Summary The National Cancer Institute's Clinical Proteomic Tumor Analysis Consortium
(CPTAC) investigates tumors from a proteogenomic perspective, creating rich multi-omics …
(CPTAC) investigates tumors from a proteogenomic perspective, creating rich multi-omics …
Cancer proteogenomics: current impact and future prospects
Genomic analyses in cancer have been enormously impactful, leading to the identification of
driver mutations and development of targeted therapies. But the functions of the vast majority …
driver mutations and development of targeted therapies. But the functions of the vast majority …
Glycan-specific molecularly imprinted polymers towards cancer diagnostics: merits, applications, and future perspectives
P Li, Z Liu - Chemical Society Reviews, 2024 - pubs.rsc.org
Aberrant glycans are a hallmark of cancer states. Notably, emerging evidence has
demonstrated that the diagnosis of cancers with tumour-specific glycan patterns holds great …
demonstrated that the diagnosis of cancers with tumour-specific glycan patterns holds great …
[HTML][HTML] Aberrant protein glycosylation: Implications on diagnosis and Immunotherapy
R Bangarh, C Khatana, S Kaur, A Sharma… - Biotechnology …, 2023 - Elsevier
Glycosylation-mediated post-translational modification is critical for regulating many
fundamental processes like cell division, differentiation, immune response, and cell-to-cell …
fundamental processes like cell division, differentiation, immune response, and cell-to-cell …
[HTML][HTML] Ovarian cancer in the era of immune checkpoint inhibitors: state of the art and future perspectives
BA Maiorano, MFP Maiorano, D Lorusso, E Maiello - Cancers, 2021 - mdpi.com
Simple Summary Ovarian cancer (OC) represents the fifth leading cause of cancer-related
deaths among women. In the advanced disease setting, OC recurrence after chemotherapy …
deaths among women. In the advanced disease setting, OC recurrence after chemotherapy …
[HTML][HTML] Roles of glycosylation at the cancer cell surface: opportunities for large scale glycoproteomics
Cell surface glycosylation has a variety of functions, and its dysregulation in cancer
contributes to impaired signaling, metastasis and the evasion of the immune responses …
contributes to impaired signaling, metastasis and the evasion of the immune responses …
Critical considerations in N-glycoproteomics
TH Chau, A Chernykh, R Kawahara… - Current Opinion in …, 2023 - Elsevier
N-Glycoproteomics, the system-wide study of glycans asparagine-linked to protein carriers,
holds a unique and still largely untapped potential to provide deep insights into the …
holds a unique and still largely untapped potential to provide deep insights into the …
[HTML][HTML] Hydrophilic interaction chromatography–mass spectrometry for metabolomics and proteomics: state-of-the-art and current trends
I Kohler, M Verhoeven, R Haselberg… - Microchemical Journal, 2022 - Elsevier
Among all the–omics approaches, proteomics and metabolomics have received increased
attention over the last decade. Both approaches have reached a certain level of maturity …
attention over the last decade. Both approaches have reached a certain level of maturity …
[HTML][HTML] pGlycoQuant with a deep residual network for quantitative glycoproteomics at intact glycopeptide level
S Kong, P Gong, WF Zeng, B Jiang, X Hou… - Nature …, 2022 - nature.com
Large-scale intact glycopeptide identification has been advanced by software tools.
However, tools for quantitative analysis remain lagging behind, which hinders exploring the …
However, tools for quantitative analysis remain lagging behind, which hinders exploring the …