Neuroanatomy of the extended circadian rhythm system
LP Morin - Experimental neurology, 2013 - Elsevier
The suprachiasmatic nucleus (SCN), site of the primary clock in the circadian rhythm system,
has three major afferent connections. The most important consists of a retinohypothalamic …
has three major afferent connections. The most important consists of a retinohypothalamic …
Multi-target strategies for the improved treatment of depressive states: conceptual foundations and neuronal substrates, drug discovery and therapeutic application
MJ Millan - Pharmacology & therapeutics, 2006 - Elsevier
Major depression is a debilitating and recurrent disorder with a substantial lifetime risk and a
high social cost. Depressed patients generally display co-morbid symptoms, and depression …
high social cost. Depressed patients generally display co-morbid symptoms, and depression …
[HTML][HTML] Neural control of the upper airway: respiratory and state-dependent mechanisms
L Kubin - Comprehensive Physiology, 2016 - ncbi.nlm.nih.gov
Upper airway muscles subserve many essential for survival orofacial behaviors, including
their important role as accessory respiratory muscles. In the face of certain predisposition of …
their important role as accessory respiratory muscles. In the face of certain predisposition of …
Pedunculopontine nucleus degeneration contributes to both motor and non-motor symptoms of Parkinson's disease
NE Chambers, K Lanza, C Bishop - Frontiers in Pharmacology, 2020 - frontiersin.org
Parkinson's disease (PD) is a neurodegenerative disorder characterized by hypokinetic
motor features; however, patients also display non-motor symptoms like sleep disorders …
motor features; however, patients also display non-motor symptoms like sleep disorders …
Pontine cholinergic mechanisms and their impact on respiratory regulation
L Kubin, V Fenik - Respiratory physiology & neurobiology, 2004 - Elsevier
Activation of pontomedullary cholinergic neurons may directly and indirectly cause
depression of respiratory motoneuronal activity, activation of respiratory premotor neurons …
depression of respiratory motoneuronal activity, activation of respiratory premotor neurons …
[HTML][HTML] The mesopontine tegmentum in reward and aversion: from cellular heterogeneity to behaviour
R Bastos-Gonçalves, B Coimbra… - … & Biobehavioral Reviews, 2024 - Elsevier
The mesopontine tegmentum, comprising the pedunculopontine tegmentum (PPN) and the
laterodorsal tegmentum (LDT), is intricately connected to various regions of the basal …
laterodorsal tegmentum (LDT), is intricately connected to various regions of the basal …
Rapid eye movement sleep induction by microinjection of the GABA-A antagonist bicuculline into the dorsal subcoeruleus area of the rat
MS Pollock, RE Mistlberger - Brain research, 2003 - Elsevier
In cats, rapid eye movement sleep (REMS) can be induced rapidly and reliably by injections
of the cholinergic agonist carbachol into the anterodorsal pontine tegmentum, also …
of the cholinergic agonist carbachol into the anterodorsal pontine tegmentum, also …
5-HT1A receptor-responsive pedunculopontine tegmental neurons suppress REM sleep and respiratory motor activity
Serotonin type 1A (5-HT1A) receptor-responsive neurons in the pedunculopontine
tegmental nucleus (PPTn) become maximally active immediately before and during rapid …
tegmental nucleus (PPTn) become maximally active immediately before and during rapid …
Efficacy of vestipitant, a neurokinin-1 receptor antagonist, in primary insomnia
E Ratti, DJ Carpenter, S Zamuner, S Fernandes… - Sleep, 2013 - academic.oup.com
Abstract Study Objectives: Investigate the hypnotic effects of repeated doses of neurokinin-1
receptor antagonist, vestipitant, in primary insomnia. Design: Randomized, double-blind …
receptor antagonist, vestipitant, in primary insomnia. Design: Randomized, double-blind …
Internal pallidum and substantia nigra control different parts of the mesopontine reticular formation in primate
AS Rolland, C Karachi, MP Muriel… - Movement …, 2011 - Wiley Online Library
The locomotor area has recently emerged as a target for deep brain stimulation to lessen
gait disturbances in advanced parkinsonian patients. An important step in choosing this …
gait disturbances in advanced parkinsonian patients. An important step in choosing this …