Post-transcriptional control of miRNA biogenesis
G Michlewski, JF Cáceres - Rna, 2019 - rnajournal.cshlp.org
MicroRNAs (miRNAs) are important regulators of gene expression that bind complementary
target mRNAs and repress their expression. Precursor miRNA molecules undergo nuclear …
target mRNAs and repress their expression. Precursor miRNA molecules undergo nuclear …
The interaction of circRNAs and RNA binding proteins: an important part of circRNA maintenance and function
J Zang, D Lu, A Xu - Journal of neuroscience research, 2020 - Wiley Online Library
The widespread expression of circular RNAs (circRNAs) is regarded as a feature of gene
expression in highly diverged eukaryotes. Recent studies have shown that circRNAs can act …
expression in highly diverged eukaryotes. Recent studies have shown that circRNAs can act …
[PDF][PDF] m6A demethylase ALKBH5 maintains tumorigenicity of glioblastoma stem-like cells by sustaining FOXM1 expression and cell proliferation program
The dynamic and reversible N 6-methyladenosine (m 6 A) RNA modification installed and
erased by N 6-methyltransferases and demethylases regulates gene expression and cell …
erased by N 6-methyltransferases and demethylases regulates gene expression and cell …
[HTML][HTML] A network of noncoding regulatory RNAs acts in the mammalian brain
Noncoding RNAs (ncRNAs) play increasingly appreciated gene-regulatory roles. Here, we
describe a regulatory network centered on four ncRNAs—a long ncRNA, a circular RNA …
describe a regulatory network centered on four ncRNAs—a long ncRNA, a circular RNA …
[HTML][HTML] Circular RNAs in cancer: opportunities and challenges in the field
Circular RNA (circRNA) is a novel member of the noncoding cancer genome with distinct
properties and diverse cellular functions, which is being explored at a steadily increasing …
properties and diverse cellular functions, which is being explored at a steadily increasing …
Nuclear long noncoding RNAs: key regulators of gene expression
A significant portion of the human genome encodes genes that transcribe long nonprotein-
coding RNAs (lncRNAs). A large number of lncRNAs localize in the nucleus, either enriched …
coding RNAs (lncRNAs). A large number of lncRNAs localize in the nucleus, either enriched …
[HTML][HTML] Circular RNA circRHOBTB3 represses metastasis by regulating the HuR-mediated mRNA stability of PTBP1 in colorectal cancer
J Chen, Y Wu, X Luo, D Jin, W Zhou, Z Ju, D Wang… - Theranostics, 2021 - ncbi.nlm.nih.gov
Background: Tumor metastasis of colorectal cancer (CRC) is the main cause of death in
most patients and the major difficulty in comprehensive CRC treatment. Circular RNAs …
most patients and the major difficulty in comprehensive CRC treatment. Circular RNAs …
What are 3′ UTRs doing?
C Mayr - Cold Spring Harbor perspectives in biology, 2019 - cshperspectives.cshlp.org
SUMMARY 3′ untranslated regions (3′ UTRs) of messenger RNAs (mRNAs) are best
known to regulate mRNA-based processes, such as mRNA localization, mRNA stability, and …
known to regulate mRNA-based processes, such as mRNA localization, mRNA stability, and …
Identification of HuR target circular RNAs uncovers suppression of PABPN1 translation by CircPABPN1
HuR influences gene expression programs and hence cellular phenotypes by binding to
hundreds of coding and noncoding linear RNAs. However, whether HuR binds to circular …
hundreds of coding and noncoding linear RNAs. However, whether HuR binds to circular …
Regulation by 3′-untranslated regions
C Mayr - Annual review of genetics, 2017 - annualreviews.org
3′-untranslated regions (3′-UTRs) are the noncoding parts of mRNAs. Compared to
yeast, in humans, median 3′-UTR length has expanded approximately tenfold alongside …
yeast, in humans, median 3′-UTR length has expanded approximately tenfold alongside …