[HTML][HTML] Immune checkpoint inhibitors in 10 years: contribution of basic research and clinical application in cancer immunotherapy

JB Lee, HR Kim, SJ Ha - Immune Network, 2022 - ncbi.nlm.nih.gov
Targeting immune evasion via immune checkpoint pathways has changed the treatment
paradigm in cancer. Since CTLA-4 antibody was first approved in 2011 for treatment of …

Non-small cell lung cancer: Emerging molecular targeted and immunotherapeutic agents

T Singh, MF Hassanabad, AF Hassanabad - Biochimica et Biophysica Acta …, 2021 - Elsevier
Non-small cell lung cancer (NSCLC) represents the most common and fatal type of primary
lung malignancies. NSCLC is often diagnosed at later stages and requires systemic …

Combining variant detection and fragment length analysis improves detection of minimal residual disease in postsurgery circulating tumour DNA of stage II–IIIA …

DCL Vessies, MMF Schuurbiers… - Molecular …, 2022 - Wiley Online Library
Stage II–IIIA nonsmall cell lung cancer (NSCLC) patients receive adjuvant chemotherapy
after surgery as standard‐of‐care treatment, even though only approximately 5.8% of …

Immunotherapy-chemotherapy combinations for non-small cell lung cancer: current trends and future perspectives

E Cella, L Zullo, S Marconi, G Rossi… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction In recent years, immunotherapy has become a pillar in the treatment of
advanced, non-oncogene-addicted non-small cell lung cancer (NSCLC). Programmed …

Real-world experience with capmatinib in MET exon 14-mutated non-small cell lung cancer (RECAP): a retrospective analysis from an early access program

O Illini, H Fabikan, A Swalduz… - … in medical oncology, 2022 - journals.sagepub.com
Background: Patients with non-small cell lung cancer (NSCLC) presenting with
mesenchymal–epithelial transition (MET) exon 14 skipping mutation have an unfavorable …

Killer to cure: Expression and production costs calculation of tobacco plant‐made cancer‐immune checkpoint inhibitors

LA Ridgley, N Falci Finardi… - Plant Biotechnology …, 2023 - Wiley Online Library
Immune checkpoint inhibitors (ICIs) have achieved huge clinical success. However, many
still have limited response rates, and are prohibitively costly. There is a need for effective …

[HTML][HTML] Refining patient selection for breast cancer immunotherapy: beyond PD-L1

M Kossai, N Radosevic-Robin, F Penault-Llorca - ESMO open, 2021 - Elsevier
Therapies that modulate immune response to cancer, such as immune checkpoint inhibitors,
began an intense development a few years ago; however, in breast cancer (BC), the results …

The influence of cancer stem cells on the risk of relapse in adenocarcinoma and squamous cell carcinoma of the lung: a prospective cohort study

V Masciale, F Banchelli, G Grisendi… - Stem Cells …, 2022 - academic.oup.com
Purpose Lung cancer relapse may be associated with the presence of a small population of
cancer stem cells (CSCs) with unlimited proliferative potential. Our study assessed the …

[HTML][HTML] Surgical outcomes after neoadjuvant chemoimmunotherapy for resectable non-small cell lung cancer

Y Hu, SY Ren, RY Wang, C Zeng, JN Li, P Xiao… - Frontiers in …, 2021 - frontiersin.org
Background Neoadjuvant chemoimmunotherapy for resectable non-small cell lung cancer
(NSCLC) represents an important research topic. Despite the potential benefits of this …

Neoadjuvant and adjuvant immunotherapy in non-small cell lung cancer—Clinical trials experience

I Chmielewska, K Stencel, E Kalinka, R Ramlau… - Cancers, 2021 - mdpi.com
Simple Summary Surgical resection remains the gold standard of early-stage non-small cell
lung cancer (NSCLC) treatment. However, only a minority of resected patients remain …