Incidence of osteonecrosis of the jaw in patients with multiple myeloma and breast or prostate cancer on intravenous bisphosphonate therapy

EP Wang, LB Kaban, GJ Strewler, N Raje… - Journal of Oral and …, 2007 - Elsevier
PURPOSE: Osteonecrosis of the jaw (ONJ) has been observed recently in patients with
cancer who are receiving intravenous bisphosphonate (BP) therapy. The incidence of BP …

Bisphosphonate‐related osteonecrosis of the jaw: an overview

SL Ruggiero - Annals of the New York Academy of Sciences, 2011 - Wiley Online Library
Bisphosphonates are widely used in the management of metastatic disease to bone and in
diseases of altered bone turnover. Recently, multiple‐case series and retrospective studies …

Osteonecrosis of the maxilla and mandible in patients with advanced cancer treated with bisphosphonate therapy

CL Estilo, CH Van Poznak, T Wiliams, GC Bohle… - The …, 2008 - academic.oup.com
Cases of osteonecrosis of the jaw (ONJ) have been reported with an increasing frequency
over the past 5 years. ONJ is most often identified in patients with cancer who are receiving …

Osteonecrosis of the jaws and bisphosphonate therapy

SL Ruggiero, SJ Drew - Journal of dental research, 2007 - journals.sagepub.com
Bisphosphonates are a class of agents used to treat osteoporosis and malignant bone
metastases. The efficacy of these agents in treating and preventing the significant skeletal …

Clinical, radiographic, and biochemical characterization of multiple myeloma patients with osteonecrosis of the jaw

N Raje, SB Woo, K Hande, JT Yap, PG Richardson… - Clinical Cancer …, 2008 - AACR
Purpose: Osteonecrosis of the jaw (ONJ) has been reported in patients with a history of
aminobisphosphonate use. This study was conducted in order to define ONJ clinically and …

Predicting risk for bisphosphonate-related osteonecrosis of the jaws: CTX versus radiographic markers

KE Fleisher, G Welch, S Kottal, RG Craig… - Oral Surgery, Oral …, 2010 - Elsevier
BACKGROUND AND OBJECTIVE: The most common risk factor for bisphosphonate-related
osteonecrosis of the jaws (BRONJ) is dentoalveolar surgery. It has been suggested that …

Incidence of osteonecrosis of the jaw in women with postmenopausal osteoporosis in the health outcomes and reduced incidence with zoledronic acid once yearly …

JT Grbic, R Landesberg, SQ Lin, P Mesenbrink… - The Journal of the …, 2008 - Elsevier
Background The authors determined incidence of osteonecrosis of the jaw (ONJ) in a large,
prospective three-year clinical trial of zoledronic acid in women with postmenopausal …

Bisphosphonate-related osteonecrosis of the jaw: diagnosis, prevention, and management

SL Ruggiero, B Mehrotra - Annual review of medicine, 2009 - annualreviews.org
Bisphosphonate therapy has been considered standard therapy in the management and
care of cancer patients with metastatic bone disease and patients with osteoporosis. The …

Pathophysiology, risk factors and management of bisphosphonate-associated osteonecrosis of the jaw: is there a diverse relationship of amino-and non …

IJ Diel, I Fogelman, B Al-Nawas, B Hoffmeister… - Critical reviews in …, 2007 - Elsevier
Reports of osteonecrosis of the jaw (ONJ) in patients receiving long-term bisphosphonate
therapy have appeared in the literature since 2003. This condition involves avascular …

Bisphosphonates and time to osteonecrosis development

PK Palaska, V Cartsos, AI Zavras - The oncologist, 2009 - academic.oup.com
Abstract Learning Objectives After completing this course, the reader will be able to:
Evaluate the current state of knowledge regarding risk of osteonecrosis of the jaw as it …