Background: Bisphosphonates are widely used for the treatment of bone diseases.
Bisphosphonate-associated osteomyelitis of the jaw (BAOMJ) affects 1 per 100,000 patients …

Purpose The main causes for the occurrence of bisphosphonate-related osteonecrosis of
the jaws (BRONJ) are the application of aminobisphosphonates and the extraction of teeth …

Osteonecrosis of the Jaw (ONJ) is a recently recognised and potentially highly morbid
complication of bisphosphonate therapy in the setting of metastatic malignancy, including …

Since the first description of bone necrosis in patients receiving bisphosphonate therapy in
2004, there have been multiple retrospective, prospective, and case-control studies that …

Objective: To review the risk of osteonecrosis of the jaw associated with bisphosphonates.
Data Sources: A MEDLINE search (1966–January 2007) and a search of international …

The US Food and Drug Administration-approved oral bisphosphonates: etidronate in 1977,
alendronate in 1995; the intravenous bisphosphonates pamidronate was marketed in 1991 …

Using jaw surgery as a surrogate marker for osteonecrosis of the jaw, this exploratory study
did not find that the risk of jaw surgery was significantly increased with the use of oral …

Bisphosphonates are the current mainstay of treatment for postmenopausal osteoporosis.
Although daily oral dosing is effective, it is associated with poor compliance, partly because …

Almost every system in the body bears the brunt from longstanding diabetes mellitus (DM).
One of its profound, devastating effects is on the musculoskeletal system. This article …

A 65-year-old woman was seen in the oral surgery clinic because of a nonhealing ulcer of
the mandible at the site of a tooth that had been extracted 3 years earlier. The patient had …