Advances in the development of biomarkers for epilepsy

A Pitkänen, W Löscher, A Vezzani, AJ Becker… - The Lancet …, 2016 - thelancet.com
Over 50 million people worldwide have epilepsy. In nearly 30% of these cases, epilepsy
remains unsatisfactorily controlled despite the availability of over 20 antiepileptic drugs …

MicroRNAs in epilepsy: pathophysiology and clinical utility

DC Henshall, HM Hamer, RJ Pasterkamp… - The Lancet …, 2016 - thelancet.com
Background Temporal lobe epilepsy is a common and frequently intractable seizure
disorder. Its pathogenesis is thought to involve large-scale alterations to the expression of …

Эпилепсия у детей и взрослых женщин и мужчин

ВА Карлов - 2019 - elibrary.ru
В руководстве представлены результаты 60-летней работы автора в области детской
и взрослой неврологии и эпилептологии. Впервые эпилептология представлена в …

Advances in the potential biomarkers of epilepsy

D Kobylarek, P Iwanowski, Z Lewandowska… - Frontiers in …, 2019 - frontiersin.org
Epilepsy is a group of chronic neurological disorders characterized by recurrent,
spontaneous, and unpredictable seizures. It is one of the most common neurological …

Dietary nutrition for neurological disease therapy: Current status and future directions

XY Mao, XX Yin, QW Guan, QX Xia, N Yang… - Pharmacology & …, 2021 - Elsevier
Adequate food intake and relative abundance of dietary nutrients have undisputed effects on
the brain function. There is now substantial evidence that dietary nutrition aids in the …

Cerebrospinal fluid microRNAs are potential biomarkers of temporal lobe epilepsy and status epilepticus

R Raoof, EM Jimenez-Mateos, S Bauer… - Scientific reports, 2017 - nature.com
There is a need for diagnostic biomarkers of epilepsy and status epilepticus to support
clinical examination, electroencephalography and neuroimaging. Extracellular microRNAs …

Down regulation of miR‐218, miR‐124, and miR‐144 relates to Parkinson's disease via activating NF‐κB signaling

RX Xing, LG Li, XW Liu, BX Tian… - The Kaohsiung Journal …, 2020 - Wiley Online Library
Parkinson's disease (PD) is a neurological degenerative disorder that is partially induced by
inflammation in the neural system. To explore the roles of disordered microRNAs in the …

Identifying and targeting angiogenesis-related microRNAs in ovarian cancer

X Chen, LS Mangala, L Mooberry, E Bayraktar… - Oncogene, 2019 - nature.com
Current anti-angiogenic therapy for cancer is based mainly on inhibition of the vascular
endothelial growth factor pathway. However, due to the transient and only modest benefit …

MicroRNA‐induced silencing in epilepsy: opportunities and challenges for clinical application

D Tiwari, K Peariso, C Gross - Developmental Dynamics, 2018 - Wiley Online Library
MicroRNAs are master regulators of gene expression. Single microRNAs influence multiple
proteins within diverse molecular pathways and networks. Therefore, changes in levels or …

Silencing rno-miR-155-5p in rat temporal lobe epilepsy model reduces pathophysiological features and cell apoptosis by activating Sestrin-3

LG Huang, J Zou, QC Lu - Brain Research, 2018 - Elsevier
Temporal lobe epilepsy (TLE) is a chronic neurological disease characterized by recurrent
spontaneous seizures. MicroRNAs are dysregulated in various pathological conditions …