Cryptococcus neoformans and Cryptococcus gattii are the two etiologic agents of
cryptococcosis. They belong to the phylum Basidiomycota and can be readily distinguished …

The incidence of invasive mycoses is increasing, especially among patients who are
immunocompromised or hospitalized with serious underlying diseases. Such infections may …

Pathogenic fungi have become a leading cause of human mortality due to the increasing
frequency of fungal infections in immunocompromised populations and the limited …

Although Cryptococcus neoformans and cryptococcosis have existed for several millennia, a
century has passed since the discovery of this encapsulated yeast and its devastating …

Fungi cause serious infections in the immunocompromised and debilitated, and the
incidence of invasive mycoses has increased significantly over the last 3 decades. Slow …

Cryptococcus neoformans is a haploid environmental organism and the major cause of
fungal meningoencephalitis in AIDS patients. Fluconazole (FLC), a triazole, is widely used …

Cryptococcus neoformans is an opportunistic fungal pathogen that causes cryptococcal
meningoencephalitis, particularly in immunocompromised patients. The fungal cell wall is an …

Pathogenic fungi are the cause of life-threatening infections in an increasing number of
immunocompromised patients. The intrinsic resistance to antifungal therapy observed in …

During the past two decades invasive fungal infections have emerged as major causes of
morbidity and mortality in immunocompromised patients. Several factors have contributed to …

The survival of all organisms depends critically upon interactions with the environment,
mediated largely through the action of small molecules. Small molecules can provide the …