Tn7: smarter than we thought
A notable feature of transposable elements—segments of DNA that can move from one
position to another in genomes—is that they are highly prevalent, despite the fact that their …
position to another in genomes—is that they are highly prevalent, despite the fact that their …
The Tn3‐family of Replicative Transposons
E Nicolas, M Lambin, D Dandoy, C Galloy… - Mobile DNA …, 2015 - Wiley Online Library
The ampicillin‐resistance transposon Tn3is the archetype (“Tn3” being synonymous with
“Tn1” or “Tn2”;(1)) of a large and widespread family of transposons with representatives in …
“Tn1” or “Tn2”;(1)) of a large and widespread family of transposons with representatives in …
Selective TnsC recruitment enhances the fidelity of RNA-guided transposition
Bacterial transposons are pervasive mobile genetic elements that use distinct DNA-binding
proteins for horizontal transmission. For example, Escherichia coli Tn 7 homes to a specific …
proteins for horizontal transmission. For example, Escherichia coli Tn 7 homes to a specific …
Structure of the TnsB transposase-DNA complex of type VK CRISPR-associated transposon
F Tenjo-Castaño, N Sofos, B López-Méndez… - Nature …, 2022 - nature.com
CRISPR-associated transposons (CASTs) are mobile genetic elements that co-opted
CRISPR-Cas systems for RNA-guided transposition. Here we present the 2.4 Å cryo-EM …
CRISPR-Cas systems for RNA-guided transposition. Here we present the 2.4 Å cryo-EM …
Structural basis for DNA targeting by the Tn7 transposon
Tn7 transposable elements are unique for their highly specific, and sometimes
programmable, target-site selection mechanisms and precise insertions. All the elements in …
programmable, target-site selection mechanisms and precise insertions. All the elements in …
Applications of transposon-based gene delivery system in bacteria
KH Choi, KJ Kim - Journal of microbiology and biotechnology, 2009 - koreascience.kr
Mobile genetic segments, or transposons, are also referred to as jumping genes as they can
shift from one position in the genome to another, thus inducing a chromosomal mutation …
shift from one position in the genome to another, thus inducing a chromosomal mutation …
[HTML][HTML] Target DNA structure plays a critical role in Tn7 transposition
The bacterial transposon Tn7 utilizes four Tn7-encoded proteins, TnsA, TnsB, TnsC and
TnsD, to make insertions at a specific site termed attTn7. This target is selected by the …
TnsD, to make insertions at a specific site termed attTn7. This target is selected by the …
Conformational landscape of the type VK CRISPR-associated transposon integration assembly
F Tenjo-Castaño, N Sofos, LS Stutzke, P Temperini… - Molecular Cell, 2024 - cell.com
CRISPR-associated transposons (CASTs) are mobile genetic elements that co-opt CRISPR-
Cas systems for RNA-guided DNA transposition. CASTs integrate large DNA cargos into the …
Cas systems for RNA-guided DNA transposition. CASTs integrate large DNA cargos into the …
Transposition into replicating DNA occurs through interaction with the processivity factor
The bacterial transposon Tn7 directs transposition into actively replicating DNA by a
mechanism involving the transposon-encoded protein TnsE. Here we show that TnsE …
mechanism involving the transposon-encoded protein TnsE. Here we show that TnsE …