Given that hypoxia is a persistent physiological feature of many different solid tumors and a
key driver for cancer malignancy, it is thought to be a major target in cancer treatment …

The introduction of second-generation androgen receptor antagonists (SG-ARAs) has
greatly impacted the treatment of metastatic prostate cancer, providing tolerable and …

Innate and adaptive immune cells patrol and survey throughout the human body and
sometimes reside in the tumor microenvironment (TME) with a variety of cell types and …

Nanomedicine offered hope for improving the treatment of cancer but the survival benefits of
the clinically approved nanomedicines are modest in many cases when compared to …

Cancer is still one of the world's deadliest health concern. As per latest statistics: lung,
breast, liver, prostate and cervical cancers are reported topmost worldwide. Although …

Cancer as a disease possess quite complicated pathophysiological implications and is
among the prominent causes of morbidity and mortality on global scales. Anti-cancer …

Introduction Cancer has been identified as one of the leading causes of death worldwide.
The biological target of some anticancer agents is topoisomerase I, an enzyme involved in …

Cancer has posed an enormous challenge to human health. To enhance cancer therapy,
researchers have constructed the polyprodrug which drug molecules and polymer backbone …

Simple Summary Low oxygen tension (hypoxia) caused by high demand of cancer cell
proliferation or standard of care therapy is a prevalent feature of solid tumors and is often …

Background Despite the clinical efficacy of enzalutamide monotherapy in patients with
advanced prostate cancer, therapeutic resistance and disease progression are inevitable …