Intracellular bacteria in cancer—prospects and debates

L Schorr, M Mathies, E Elinav, J Puschhof - npj Biofilms and …, 2023 - nature.com
Recent evidence suggests that some human cancers may harbor low-biomass microbial
ecosystems, spanning bacteria, viruses, and fungi. Bacteria, the most-studied kingdom in …

Bacteria-based immunotherapy for cancer: a systematic review of preclinical studies

M Zhou, Y Tang, W Xu, X Hao, Y Li, S Huang… - Frontiers in …, 2023 - frontiersin.org
Immunotherapy has been emerging as a powerful strategy for cancer management.
Recently, accumulating evidence has demonstrated that bacteria-based immunotherapy …

[HTML][HTML] The significant clinical correlation of the intratumor oral microbiome in oral squamous cell carcinoma based on tissue-derived sequencing

Z Li, R Fu, X Wen, Q Wang, X Huang… - Frontiers in Physiology, 2023 - frontiersin.org
Background: The microbiota is a critical component of the complex human
microenvironment, impacting various physiological processes and disease development via …

Remotely Controllable Supramolecular Nanomedicine for Drug‐Resistant Colorectal Cancer Therapy Caused by Fusobacterium nucleatum

X Yan, Y Xin, Y Yu, X Li, B Li, M Elsabahy… - Small …, 2024 - Wiley Online Library
Fusobacterium nucleatum (Fn) existing in the community of colorectal cancer (CRC)
promotes CRC progression and causes chemotherapy resistance. Despite great efforts that …

The emerging role of the gut microbiome in cancer cell plasticity and therapeutic resistance

P Mondal, SM Meeran - Cancer and Metastasis Reviews, 2024 - Springer
Resistance to therapeutic agents is one of the major challenges in cancer therapy.
Generally, the focus is given to the genetic driver, especially the genetic mutation behind the …

Unlocking the secrets: exploring the influence of the aryl hydrocarbon receptor and microbiome on cancer development

M Rayan, TS Sayed, OJ Hussein, L Therachiyil… - Cellular & Molecular …, 2024 - Springer
Gut microbiota regulates various aspects of human physiology by producing metabolites,
metabolizing enzymes, and toxins. Many studies have linked microbiota with human health …

Intratumour microbiota modulates adrenocortical cancer responsiveness to mitotane

G Cantini, E Niccolai, L Canu… - Endocrine-Related …, 2023 - erc.bioscientifica.com
The infiltrating microbiota represents a novel cellular component of the solid tumour
microenvironment that can influence tumour progression and response to therapy …

Microbiomes, Their Function, and Cancer: How Metatranscriptomics Can Close the Knowledge Gap

L Aitmanaitė, K Širmonaitis, G Russo - International journal of molecular …, 2023 - mdpi.com
The interaction between the microbial communities in the human body and the onset and
progression of cancer has not been investigated until recently. The vast majority of the …

[HTML][HTML] Circulating microbiome DNA as biomarkers for early diagnosis and recurrence of lung cancer

H Chen, Y Ma, J Xu, W Wang, H Lu, C Quan… - Cell Reports …, 2024 - cell.com
Lung cancer mortality is exacerbated by late-stage diagnosis. Emerging evidence indicates
the potential clinical significance of distinct microbial signatures as diagnostic and …

Tumor Microbial Communities and Thyroid Cancer Development—The Protective Role of Antioxidant Nutrients: Application Strategies and Future Directions

F Gorini, A Tonacci - Antioxidants, 2023 - mdpi.com
Thyroid cancer (TC), the most frequent malignancy of the endocrine system, has recorded
an increasing incidence in the last decades. The etiology of TC remains at least partly …