Immediate and long-term consequences of COVID-19 infections for the development of neurological disease
Increasing evidence suggests that infection with Sars-CoV-2 causes neurological deficits in
a substantial proportion of affected patients. While these symptoms arise acutely during the …
a substantial proportion of affected patients. While these symptoms arise acutely during the …
Cytokines in inflammatory disease
This review aims to briefly discuss a short list of a broad variety of inflammatory cytokines.
Numerous studies have implicated that inflammatory cytokines exert important effects with …
Numerous studies have implicated that inflammatory cytokines exert important effects with …
Effect of colchicine vs standard care on cardiac and inflammatory biomarkers and clinical outcomes in patients hospitalized with coronavirus disease 2019: the …
Importance Severe acute respiratory syndrome coronavirus 2 infection has evolved into a
global pandemic. Low-dose colchicine combines anti-inflammatory action with a favorable …
global pandemic. Low-dose colchicine combines anti-inflammatory action with a favorable …
Novel coronavirus-induced NLRP3 inflammasome activation: a potential drug target in the treatment of COVID-19
A Shah - Frontiers in immunology, 2020 - frontiersin.org
Novel coronaviruses (nCoVs) encode ion-channel proteins called viroporins such as protein
E, open reading frame 3a (ORF3a) and ORF8a. These viroporins, via mechanisms such as …
E, open reading frame 3a (ORF3a) and ORF8a. These viroporins, via mechanisms such as …
The acute respiratory distress syndrome: from mechanism to translation
SH Han, RK Mallampalli - The Journal of Immunology, 2015 - journals.aai.org
The acute respiratory distress syndrome (ARDS) is a form of severe hypoxemic respiratory
failure that is characterized by inflammatory injury to the alveolar capillary barrier, with …
failure that is characterized by inflammatory injury to the alveolar capillary barrier, with …
[HTML][HTML] The Greek study in the effects of colchicine in COvid-19 complications prevention (GRECCO-19 study): Rationale and study design
Objective Colchicine has been utilized safely in a variety of cardiovascular clinical
conditions. Among its potential mechanisms of action is the non-selective inhibition of …
conditions. Among its potential mechanisms of action is the non-selective inhibition of …
Innate receptor activation patterns involving TLR and NLR synergisms in COVID-19, ALI/ARDS and sepsis cytokine storms: a review and model making novel …
R Root-Bernstein - International journal of molecular sciences, 2021 - mdpi.com
Severe COVID-19 is characterized by a “cytokine storm”, the mechanism of which is not yet
understood. I propose that cytokine storms result from synergistic interactions among Toll …
understood. I propose that cytokine storms result from synergistic interactions among Toll …
Neutrophil extracellular traps augmented alveolar macrophage pyroptosis via AIM2 inflammasome activation in LPS-induced ALI/ARDS
H Li, Y Li, C Song, Y Hu, M Dai, B Liu… - Journal of Inflammation …, 2021 - Taylor & Francis
Background Uncontrollable inflammation is a critical feature of gram-negative bacterial
pneumonia-induced acute respiratory distress syndrome (ARDS). Both neutrophils and …
pneumonia-induced acute respiratory distress syndrome (ARDS). Both neutrophils and …
Signaling pathways involved in paraquat-induced pulmonary toxicity: Molecular mechanisms and potential therapeutic drugs
X Liu, H Yang, Z Liu - International Immunopharmacology, 2022 - Elsevier
Paraquat poisoning is a severe health problem globally, particularly in developing countries.
Due to its severe toxicity, the mortality rate of paraquat poisoning is greatly higher than other …
Due to its severe toxicity, the mortality rate of paraquat poisoning is greatly higher than other …
[HTML][HTML] The dynamic interplay between AMPK/NFκB signaling and NLRP3 is a new therapeutic target in inflammation: Emerging role of dapagliflozin in overcoming …
Acute lung injury (ALI) is one the most common causes of morbidity and mortality in critically
ill patients. In this study, we examined for first time the role of dapagliflozin (DPGZ) in …
ill patients. In this study, we examined for first time the role of dapagliflozin (DPGZ) in …