Lipid composition of the cancer cell membrane

W Szlasa, I Zendran, A Zalesińska, M Tarek… - Journal of bioenergetics …, 2020 - Springer
Cancer cell possesses numerous adaptations to resist the immune system response and
chemotherapy. One of the most significant properties of the neoplastic cells is the altered …

An updated review of lysophosphatidylcholine metabolism in human diseases

SH Law, ML Chan, GK Marathe, F Parveen… - International journal of …, 2019 - mdpi.com
Lysophosphatidylcholine (LPC) is increasingly recognized as a key marker/factor positively
associated with cardiovascular and neurodegenerative diseases. However, findings from …

Phosphatidylcholine-derived lipid mediators: The crosstalk between cancer cells and immune cells

RF Saito, LNS Andrade, SO Bustos… - Frontiers in …, 2022 - frontiersin.org
To become resistant, cancer cells need to activate and maintain molecular defense
mechanisms that depend on an energy trade-off between resistance and essential functions …

Resveratrol contrasts LPA-induced ovarian cancer cell migration and platinum resistance by rescuing hedgehog-mediated autophagy

A Ferraresi, A Esposito, C Girone, L Vallino, A Salwa… - Cells, 2021 - mdpi.com
Background: Ovarian cancer progression and invasiveness are promoted by a range of
soluble factors released by cancer cells and stromal cells within the tumor …

Advances in lipidomics

HF Avela, H Siren - Clinica Chimica Acta, 2020 - Elsevier
The present article examines recently published literature on lipids, mainly focusing on
research involving glycero-, glycerophospho-and sphingo-lipids. The primary aim is …

ANGPTL4 accelerates ovarian serous cystadenocarcinoma carcinogenesis and angiogenesis in the tumor microenvironment by activating the JAK2/STAT3 pathway …

Y Li, A Gao, T Zeng, D Liu, Q Zhang, X Ran… - Journal of Translational …, 2024 - Springer
Background Ovarian cancer (OC) is a malignant neoplasm that displays increased
vascularization. Angiopoietin-like 4 (ANGPTL4) is a secreted glycoprotein that functions as a …

Development and validation of a novel 11-gene prognostic model for serous ovarian carcinomas based on lipid metabolism expression profile

M Zheng, H Mullikin, A Hester, B Czogalla… - International journal of …, 2020 - mdpi.com
(1) Background: Biomarkers might play a significant role in predicting the clinical outcomes
of patients with ovarian cancer. By analyzing lipid metabolism genes, future perspectives …

Targeting lysophosphatidic acid in cancer: the issues in moving from bench to bedside

Y Xu - Cancers, 2019 - mdpi.com
Since the clear demonstration of lysophosphatidic acid (LPA)'s pathological roles in cancer
in the mid-1990s, more than 1000 papers relating LPA to various types of cancer were …

The phospholipid membrane compositions of bacterial cells, cancer cell lines and biological samples from cancer patients

KLF Hilton, C Manwani, JE Boles, LJ White… - Chemical …, 2021 - pubs.rsc.org
While cancer now impacts the health and well-being of more of the human population than
ever before, the exponential rise in antimicrobial resistant (AMR) bacterial infections means …

Lipid metabolism and Calcium signaling in epithelial ovarian cancer

S Kouba, L Ouldamer, C Garcia, D Fontaine… - Cell calcium, 2019 - Elsevier
Epithelial Ovarian cancer (EOC) is the deadliest gynecologic malignancy and represents the
fifth leading cause of all cancer-related deaths in women. The majority of patients are …