Recent advances in triazoles as tyrosinase inhibitors

A Mermer, S Demirci - European Journal of Medicinal Chemistry, 2023 - Elsevier
The tyrosinase enzyme, which is widely found in microorganisms, animals and plants, has a
significant position in melanogenesis, plays an important role in undesirable browning of …

Tyrosinase inhibitors naturally present in plants and synthetic modifications of these natural products as anti-melanogenic agents: a review

M Hassan, S Shahzadi, A Kloczkowski - Molecules, 2023 - mdpi.com
Tyrosinase is a key enzyme target to design new chemical ligands against melanogenesis.
In the current review, different chemical derivatives are explored which have been used as …

[HTML][HTML] Recent advances in the conjugation approaches for enhancing the bioavailability of polyphenols

S Sahraeian, A Rashidinejad, MT Golmakani - Food Hydrocolloids, 2024 - Elsevier
In recent years, the consumption of functional foods containing health-beneficial ingredients
has become increasingly popular. Polyphenols are among the most important functional and …

Naturally-occurring tyrosinase inhibitors classified by enzyme kinetics and copper chelation

HD Kim, H Choi, F Abekura, JY Park, WS Yang… - International Journal of …, 2023 - mdpi.com
Currently, there are three major assaying methods used to validate in vitro whitening activity
from natural products: methods using mushroom tyrosinase, human tyrosinase, and …

茶多酚对酪氨酸酶的抑制作用及分子机制研究.

李帅浩, 谭充, 冯子健, 马秋越, 陈南… - Journal of Food …, 2023 - search.ebscohost.com
目的研究茶多酚对酪氨酸酶的抑制作用及分子机制. 方法通过生化分析法,
测定茶多酚对酪氨酸酶的抑制作用并分析其抑制动力学; 采用荧光光谱, 圆二色谱和分子模拟 …

Evaluating Phytochemical Profiles, Cytotoxicity, Antiviral Activity, Antioxidant Potential, and Enzyme Inhibition of Vepris boiviniana Extracts

K Bakar, Nilofar, A Mohamed, Ł Świątek, B Hryć… - Molecules, 2023 - mdpi.com
In the present study, we performed comprehensive LC-MS chemical profiling and biological
tests of Vepris boiviniana leaves and stem bark extracts of different polarities. In total, 60 …

[HTML][HTML] Expediting Multiple Biological Properties of Limonene and α-Pinene: Main Bioactive Compounds of Pistacia lentiscus L., Essential Oils

N El Omari, HN Mrabti, T Benali, R Ullah… - Frontiers in Bioscience …, 2023 - imrpress.com
Background: Screening new natural molecules with pharmacological and/or cosmetic
properties remains a highly sought-after area of research. Moreover, essential oils and …

Integration of chemical characterization, biological activities, and network pharmacology of different extracts from Syzygium rowlandii

KI Sinan, S Sut, G Zengin, S Dall'Acqua… - Journal of Molecular …, 2024 - Elsevier
The leaves and stem barks of Syzygium rowlandii, were considered as sources of
biologically active compounds. Using the ultrasound-assisted extraction with different …

Simple phenylpropanoids: recent advances in biological activities, biosynthetic pathways, and microbial production

Z Zhu, R Chen, L Zhang - Natural Product Reports, 2023 - pubs.rsc.org
Covering: 2000 to 2023 Simple phenylpropanoids are a large group of natural products with
primary C6–C3 skeletons. They are not only important biomolecules for plant growth but …

Kinetic studies, molecular docking, and antioxidant activity of novel 1, 3-diphenyl pyrazole-thiosemicarbazone with anti-tyrosinase and anti-melanogenesis properties

F Azimi, M Mahdavi, M Khoshneviszadeh, F Shafiee… - Bioorganic …, 2024 - Elsevier
This study reports the Design Hypothesis of a novel series of 1, 3-diphenyl pyrazole-
thiosemicarbazone as novel tyrosinase inhibitors (TYRI). The designed compounds were …