Synthesis and antifungal evaluation of novel triazole derivatives bearing a pyrazole-methoxyl moiety

Y Hao, R Wang, T Ni, BC Monk, JDA Tyndall… - European Journal of …, 2024 - Elsevier
Life-threatening invasive fungal infections pose a serious threat to human health. A series of
novel triazole derivatives bearing a pyrazole-methoxyl moiety were designed and …

The discovery of an anti-Candida xanthone with selective inhibition of Candida albicans GAPDH

XR Chen, T Zhou, ZD Zhou, ZH Fang, KB Wang… - International Journal of …, 2024 - Elsevier
Objectives This study aimed to discover novel antifungals targeting Candida albicans
glyceraldehyde-3-phosphate dehydrogenase (CaGAPDH), have an insight into inhibitory …

Evaluation of the antidermatophytic activity of potassium salts of N-acylhydrazinecarbodithioates and their aminotriazole-thione derivatives

A Ciesielska, A Kowalczyk, A Paneth, P Stączek - Scientific Reports, 2024 - nature.com
Nowadays, dermatophyte infections are relatively easy to cure, especially since the
introduction of orally administered antifungals such as terbinafine and itraconazole …

Synthesis and Biological Evaluation of a Series of New Hybrid Amide Derivatives of Triazole and Thiazolidine-2, 4-dione

IB Levshin, AY Simonov, AA Panov, NE Grammatikova… - Pharmaceuticals, 2024 - mdpi.com
A series of hybrid compounds with triazole and thiazolidine nuclei connected by a linker has
been synthesized and extensively studied. Various synthetic methods for the target …

Design, synthesis and evaluation of 2-phenylpyrimidine derivatives as novel antifungal agents targeting CYP51

Z Gao, J Zhang, K Li, Y Sun, X Wu, G Zhang… - RSC Medicinal …, 2024 - pubs.rsc.org
Invasive fungal infections, with high morbidity and mortality, have become one of the most
serious threats to human health. There are a few kinds of clinical antifungal drugs but large …

Palladium‐Catalyzed Three‐Component Process to [1, 2, 3] Triazolo [1, 5‐c] quinazolines

J Li, S Zhang, T Xiao, B Yang, Y Jiang - ChemistrySelect, 2024 - Wiley Online Library
An efficient palladium‐catalyzed three‐component reaction for the synthesis of tricyclic fused
1, 2, 3‐triazole derivatives from amino‐NH‐1, 2, 3‐triazoles, isocyanide and iodoarenes has …

C. albicans ERG11/C5_00660C Literature Guide

GOT Finder, GOS Mapper - candidagenome.org
C. albicans ERG11/C5_00660C Literature Guide About Site Map How to Cite Help Home Search
BLAST GO Term Finder GO Slim Mapper Text Search Primers PatMatch Advanced Search …