Regulatory T (Treg) cells play vital roles in immune homeostasis and response, including
discrimination between self-and non-self-antigens, containment of immunopathology, and …

Regulatory T (Treg) cells interact with a variety of resident cells and infiltrated immune cells
in the central nervous system (CNS) to modulate neuroinflammation and …

The discovery of FOXP3+ regulatory T (Treg) cells as a distinct cell lineage with a central
role in regulating immune responses provided a deeper understanding of self-tolerance …

Regulatory T cells (Tregs) play a crucial role in enforcing immune tolerance in the periphery,
preventing the activation of autoreactive cells, production of autoantibodies, and …

Regulatory T cells (Treg) are essential for immune balance, preventing overreactive
responses and autoimmunity. Although traditionally characterized as CD4+ CD25+ CD127 …

Regulatory T cells (Tregs) are crucial for preserving tolerance in the body, rendering Treg
immunotherapy a promising treatment option for both organ transplants and autoimmune …

Bullous pemphigoid (BP) and pemphigus vulgaris (PV) are two common subtypes of
autoimmune bullous disease (AIBD). The key role of circulating autoreactive immune cells …

Background Systemic mastocytosis (SM) is a heterogeneous disease characterized by an
expansion of KIT-mutated mast cells (MC). KIT-mutated MC display activated features and …

The immune system provides 2 layers, innate and adaptive, of defense against pathogenic
organisms or endogenous dangers. Normally, the innate immune response is rapid (minutes …

Our bodies are in continuous contact with diverse microorganisms, with most exposure
occurring at epithelial sites. The skin and digestive tract epithelia are two of the biggest …