1, 2, 3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships

Z Xu, SJ Zhao, Y Liu - European journal of medicinal chemistry, 2019 - Elsevier
Anticancer agents are critical for the cancer treatment, but side effects and the drug
resistance associated with the currently used anticancer agents create an urgent need to …

1, 2, 3-Triazole-containing compounds as anti–lung cancer agents: Current developments, mechanisms of action, and structure–activity relationship

T Liang, X Sun, W Li, G Hou, F Gao - Frontiers in pharmacology, 2021 - frontiersin.org
Lung cancer is the most common malignancy and leads to around one-quarter of all cancer
deaths. Great advances have been achieved in the treatment of lung cancer with novel …

(E)-4-((4-Bromobenzylidene) amino)-N-(Pyrimidin-2-yl) benzenesulfonamide from 4-bromobenzaldehyde and sulfadiazine, synthesis, spectral (FTIR, UV–vis) …

S Sowrirajan, N Elangovan, G Ajithkumar… - Polycyclic Aromatic …, 2022 - Taylor & Francis
Abstract (E)-4-((4-bromobenzylidene) amino)-N-(pyrimidin-2-yl) benzenesulfonamide were
synthesized with condensation of 4-bromobenzaldehyde and sulfadiazine (4BRDA). This …

Supramolecular charge-transfer complex generated by the interaction between tin (II) 2, 3-naphtalocyanine as a donor with DDQ as an acceptor: Spectroscopic …

GH Al-Hazmi, AM Hassanien, AA Atta, MS Refat… - Journal of Molecular …, 2022 - Elsevier
The charge-transfer (CT) phenomenon has attracted the attention of many researchers since
it was discovered by Robert Mulliken in 1969. Complexes generated through CT interactions …

One-pot synthesis, molecular docking, ADMET, and DFT studies of novel pyrazolines as promising SARS-CoV-2 main protease inhibitors

RHH Salih, AH Hasan, AJ Hussein, MK Samad… - Research on Chemical …, 2022 - Springer
Pyrazoline and its derivatives have numerous prominent pharmacological effects. Focusing
on its anti-viral property, we have designed and synthesized three novel pyrazoline …

Synthesis and characterization of a novel Mannich base benzimidazole derivative to explore interaction with human serum albumin and antimicrobial property …

FM Mashood Ahamed, B Shakya… - Journal of Biomolecular …, 2023 - Taylor & Francis
The novel Mannich base benzimidazole derivative (CB-1), 1-((1H-benzo [d] imidazol-1-yl)(3-
chlorophenyl) methyl)-3-phenylurea) has been designed and synthesized by reacting …

Synthesis and spectroscopic characterizations of nanostructured charge transfer complexes associated between moxifloxacin drug donor and metal chloride …

MS Refat, HA Saad, AA Gobouri, M Alsawat… - Journal of Molecular …, 2022 - Elsevier
Moxifloxacin Histidine mixed ligand (MHL) metal complexes of the M. Mof. His· nH 2 O type,
where M are (Mg (II), Ca (II), Fe (III), and Zn (II)), Mof is moxifloxacin and His is a histidine …

Synthesis, biological activities, antioxidant properties, and molecular docking studies of novel bis-schiff base podands as responsive chemosensors for anions

G Yapar, N Demir, A Kiraz, GY Özkat, M Yıldız - Journal of Molecular …, 2022 - Elsevier
In this study, bis-carbonyl podand (triethylene glycol bis (2-carbonylphenyl) ether)(1) was
synthesized from the reaction of triethylene glycol dichloride with salicylaldehyde. Then …

An overview of recent advances in the applications of click chemistry in the synthesis of bioconjugates with anticancer activities

K Mashayekh, P Shiri - ChemistrySelect, 2019 - Wiley Online Library
The click chemistry is one of the most powerful C− N bond forming‐reactions towards five‐
membered heterocycles. The copper‐catalyzed azide‐alkyne cycloaddition (CuAAC) has …

Photocatalytic activity, DFT/TD-DFT, and spectrophotometric studies of a synthesized charge transfer complex of p-toluidine with 1, 2, 4, 5-benzenetetracarboxylic acid …

IM Khan, F Naaz, S Shakya, M Islam, A Khan… - Journal of Molecular …, 2024 - Elsevier
The hydrogen bound charge transfer (CT) complex of p-toluidine (PT) and 1, 2, 4, 5-
benzenetetracarboxylic acid (BTC) was synthesized and subsequently characterized using …