In silico quantification of intersubject variability on aerosol deposition in the oral airway
The extrathoracic oral airway is not only a major mechanical barrier for pharmaceutical
aerosols to reach the lung but also a major source of variability in lung deposition. Using …
aerosols to reach the lung but also a major source of variability in lung deposition. Using …
Numerical investigation of corticosteroid aerosol transport characteristics for pediatric acute epiglottitis at different severity levels
F Yang, Y Wang, R Ma, Z Hu, J Zhao, S Sun, H Ren… - Powder Technology, 2024 - Elsevier
Inhalation therapy is widely used in the treatment of acute epiglottitis (AE). However, few
studies specifically consider the anatomical variations in pediatric AE treatment. This study …
studies specifically consider the anatomical variations in pediatric AE treatment. This study …
A computational analysis on the impact of multilevel laryngotracheal stenosis on airflow and drug particle dynamics in the upper airway
Laryngotracheal stenosis (LTS) is a type of airway narrowing that is frequently caused by
intubation-related trauma. LTS can occur at one or multiple locations in the larynx and/or …
intubation-related trauma. LTS can occur at one or multiple locations in the larynx and/or …
Modeling of inhaled corticosteroids delivery for topical croup treatment in pediatric upper airways
Y Wang, R Ma, S Sun, Z Hu, C Li, M Lou… - Journal of Drug Delivery …, 2023 - Elsevier
Croup is the most frequent cause of pediatric upper airway obstruction characterized by
spindle-shaped stenosis in the subglottis mucosa. Inhaled corticosteroids (ICSs) serve as …
spindle-shaped stenosis in the subglottis mucosa. Inhaled corticosteroids (ICSs) serve as …
A Novel Trans-Tracheostomal Retrograde Inhalation Technique Increases Subglottic Drug Deposition Compared to Traditional Trans-Oral Inhalation
Subglottic stenosis represents a challenging clinical condition in otolaryngology. Although
patients often experience improvement following endoscopic surgery, recurrence rates …
patients often experience improvement following endoscopic surgery, recurrence rates …
Dexamethasone eluting polydopaminated polycaprolactone‐poly (lactic‐co‐glycolic) acid for treatment of tracheal stenosis
Tracheal stenosis is commonly caused by injury, resulting in inflammation and fibrosis.
Inhibiting inflammation and promoting epithelization can reduce recurrence after initial …
Inhibiting inflammation and promoting epithelization can reduce recurrence after initial …
Computational model of nano-pharmacological particles for the clinical management of stenotic and aneurysmatic coronary artery in the human body
IA Fetuga, OO Olakoyejo, O Oluwatusin… - Nigerian Journal of …, 2023 - ajol.info
This work presents a three-dimensional computational study of nanoparticles (metallic and
non-metallic) suspended in blood flowing through a diseased artery with both stenosis and …
non-metallic) suspended in blood flowing through a diseased artery with both stenosis and …