The number of cost-of-illness (COI) studies has expanded considerably over time. One
outcome of this growth is that the reported COI estimates are inconsistent across studies …

The term cognitive impairment of vascular origin is used to designate global cognitive
deficits as well as focal neurological deficits such as aphasia, apraxia and agnosia of …

Background and Purpose—The presence of white matter hyperintensities on brain MRI is
common among elderly individuals. Previous research suggests that cardiovascular risk …

There are no approved symptomatic treatments for vascular dementia (VaD). Rapamycin
(RAPA) improves cognitive deficits in Alzheimer's disease rats. To explore whether RAPA …

Vascular cognitive impairment (VCI) encompasses cognitive disorders associated with
cerebrovascular disease, often manifesting as white matter lesions (WMLs), irrespective of …

A. Smallwood, A. Oulhaj, C. Joachim, S. Christie, C. Sloan, AD Smith and M. Esiri (2012)
Neuropathology and Applied Neurobiology38, 337–343 Cerebral subcortical small vessel …

This study examines the relationship between systemic vascular function, neurocognitive
performance, and structural brain abnormalities on magnetic resonance imaging (MRI) …

Research directed towards early diagnosis and therapy of dementia demands rapid
identification of prodromal mild cognitive impairment (MCI). A longitudinal study was …

Background Serum vascular endothelial growth factor (VEGF) and infarct volume detected
by brain imaging have been associated with stroke outcome. However, the relationship of …

We present new quantitative diffusion-tensor imaging (DTI) tractography-based metrics for
assessing cerebral white matter integrity. These metrics extend prior work in this area …