Patients with systemic lupus erythematosus (SLE) frequently show symptoms of central
nervous system (CNS) involvement, termed neuropsychiatric SLE (NPSLE). The CNS …

Neuropsychiatric (NP) events occur in the majority of patients with SLE and predominantly
affect the CNS in addition to the peripheral and autonomic systems. Approximately 30% of …

Cognitive dysfunction (CD) is a common yet often clinically subtle manifestation that
considerably impacts the health-related quality of life in patients with systemic lupus …

Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by
multiple immunologic abnormalities and has the potential to involve the central nervous …

Objectives To examine the association between blood-brain barrier (BBB) integrity, brain
volume and cognitive dysfunction in adult patients with systemic lupus erythematosus (SLE) …

Objective A limited range of neuropsychiatric symptoms have been reported in systemic
autoimmune rheumatic diseases (SARDs), with varied symptom prevalence. This study …

During the last decades, there has been an increased interest in the discovery and
validation of biomarkers that reliably reflect specific aspects of lupus. Although many …

Neuropsychiatric involvement of SLE includes a variety of symptoms that impact quality of
life and patient prognosis. There have been recent advances in improving the diagnosis of …

It took decades to arrive at the general consensus dismissing the notion that the immune
system is independent of the central nervous system. In the case of uncontrolled systemic …

Objectives Using a reversible multistate model, we prospectively examined neuropsychiatric
(NP) events for attribution, outcome and association with health-related quality of life …