There is an extensive spectrum of autoimmune entities that can involve the central nervous
system, which has expanded with the emergence of new imaging modalities and several …

Objective This study aimed to seek a new method of evaluation and surrogate markers for
diffuse neuropsychiatric SLE (NPSLE). Methods We enrolled 44 patients with SLE between …

Objectives The reported prevalence of mental health conditions (MHCs) in people with
systemic lupus erythematosus (SLE) ranges widely. Whether MHCs are associated with …

Background The prevalence and pathophysiological mechanisms of cognitive deficits (CD)
Systemic Lupus Erythematosus (SLE) and Rheumatoid arthritis (RA) are very …

Objective To compare cognitive function between patients with different phenotypes of
neuropsychiatric systemic lupus erythematosus (NPSLE) and assess its association with …

Microglia are resident macrophages within the central nervous system, serving as the first
responders to neuroinflammation. Glucocorticoids (GCs) may cause damage to brain tissue …

Background The short-term and long-term outcome of inflammatory neuropsychiatric SLE
(NPSLE) with immunosuppressive treatment is largely unknown. We used clinical data from …

Objectives Cognitive dysfunction (CD) and depression are interlinked comorbidities of SLE.
They may be the result of altered brain mechanisms. This study aimed to examine SLE …

Objectives Central nervous system (CNS) proteins such as neurofilament light chain (NfL)
and glial fibrillary acidic protein (GFAP) are released into the body fluids following CNS …

Background: Systemic lupus erythematosus (SLE) is a common autoimmune disease with
various symptoms involving multiple organs. Neuropsychological manifestations are various …