The intergenerational effects of parental physical activity on offspring brain and neurocognition in humans: A scoping review

SR Valkenborghs, PC Dent, CM Stillman - Neuroscience & Biobehavioral …, 2022 - Elsevier
Animal models suggest physical activity (PA) has intergenerational effects on brain health
and neurocognition. This scoping review compiles the human literature in this area …

Prenatal stress induces translational disruption associated with myelination deficits

GK Crombie, HK Palliser, JC Shaw, BA Hanley… - Dev. Neurosci, 2023 - karger.com
Disruptions to neurodevelopment are known to be linked to behavioral disorders in
childhood and into adulthood. The fetal brain is extremely vulnerable to stimuli that alter …

[HTML][HTML] How is prenatal stress transmitted from the mother to the fetus?

Y Sze, PJ Brunton - Journal of Experimental Biology, 2024 - journals.biologists.com
Prenatal stress programmes long-lasting neuroendocrine and behavioural changes in the
offspring. Often this programming is maladaptive and sex specific. For example, using a rat …

Evaluating changes in GABAergic and glutamatergic pathways in early life following prenatal stress and postnatal neurosteroid supplementation

GK Crombie, HK Palliser, JC Shaw… - …, 2022 - Elsevier
Background A correct balance of activity of the GABA and glutamate systems is vital for
optimal neurodevelopment and general CNS function, and the dysregulation of this balance …

Human pharmacokinetics of XBD173 and etifoxine distinguish their potential for pharmacodynamic effects mediated by translocator protein

DR Owen, A Phillips, D O'Connor… - British Journal of …, 2022 - Wiley Online Library
XBD173 and etifoxine are translocator protein (TSPO) ligands that modulate inflammatory
responses in preclinical models. Limited human pharmacokinetic data is available for either …

Optimization of overhead enclosure monitoring in juvenile male Dunkin Hartley guinea pigs (Cavia porcellus)

JE Helbling, AP Spittler, MJ Sadar… - Laboratory …, 2023 - journals.sagepub.com
Overhead enclosure monitoring provides objective quantitative mobility measurements for
animals undergoing open-field testing. Notably, protocols for testing optimization have been …

The Association Between Stress and Symptomatic Tinnitus: A Preliminary Study

J Yan, L Wu, Y Lv, F Pan - Ear, Nose & Throat Journal, 2024 - journals.sagepub.com
Background: Tinnitus can severely impair people's quality of life. Stress has been involved in
the pathogenesis of multiform mental disorders. Tinnitus-related annoying symptoms have a …

Optimization of overhead enclosure monitoring software in a rodent model of osteoarthritis

JE Helbling - 2022 - search.proquest.com
Osteoarthritis (OA) is a degenerative joint disease characterized by pain, inflammation, and
decreased range of motion, leading to impaired activities of daily living and reduced quality …

[HTML][HTML] Neurosteroids: A Promising Next Step Towards Treating Behavioral Disorders

A Ferguson - journals.library.columbia.edu
From alcohol addiction to anxiety, psychological illnesses are pervasive in today's society.
While scientists have long struggled to find effective and sustainable treatment methods …