The intergenerational effects of parental physical activity on offspring brain and neurocognition in humans: A scoping review
SR Valkenborghs, PC Dent, CM Stillman - Neuroscience & Biobehavioral …, 2022 - Elsevier
Animal models suggest physical activity (PA) has intergenerational effects on brain health
and neurocognition. This scoping review compiles the human literature in this area …
and neurocognition. This scoping review compiles the human literature in this area …
Prenatal stress induces translational disruption associated with myelination deficits
GK Crombie, HK Palliser, JC Shaw, BA Hanley… - Dev. Neurosci, 2023 - karger.com
Disruptions to neurodevelopment are known to be linked to behavioral disorders in
childhood and into adulthood. The fetal brain is extremely vulnerable to stimuli that alter …
childhood and into adulthood. The fetal brain is extremely vulnerable to stimuli that alter …
[HTML][HTML] How is prenatal stress transmitted from the mother to the fetus?
Y Sze, PJ Brunton - Journal of Experimental Biology, 2024 - journals.biologists.com
Prenatal stress programmes long-lasting neuroendocrine and behavioural changes in the
offspring. Often this programming is maladaptive and sex specific. For example, using a rat …
offspring. Often this programming is maladaptive and sex specific. For example, using a rat …
Evaluating changes in GABAergic and glutamatergic pathways in early life following prenatal stress and postnatal neurosteroid supplementation
GK Crombie, HK Palliser, JC Shaw… - …, 2022 - Elsevier
Background A correct balance of activity of the GABA and glutamate systems is vital for
optimal neurodevelopment and general CNS function, and the dysregulation of this balance …
optimal neurodevelopment and general CNS function, and the dysregulation of this balance …
Human pharmacokinetics of XBD173 and etifoxine distinguish their potential for pharmacodynamic effects mediated by translocator protein
DR Owen, A Phillips, D O'Connor… - British Journal of …, 2022 - Wiley Online Library
XBD173 and etifoxine are translocator protein (TSPO) ligands that modulate inflammatory
responses in preclinical models. Limited human pharmacokinetic data is available for either …
responses in preclinical models. Limited human pharmacokinetic data is available for either …
Optimization of overhead enclosure monitoring in juvenile male Dunkin Hartley guinea pigs (Cavia porcellus)
JE Helbling, AP Spittler, MJ Sadar… - Laboratory …, 2023 - journals.sagepub.com
Overhead enclosure monitoring provides objective quantitative mobility measurements for
animals undergoing open-field testing. Notably, protocols for testing optimization have been …
animals undergoing open-field testing. Notably, protocols for testing optimization have been …
The Association Between Stress and Symptomatic Tinnitus: A Preliminary Study
J Yan, L Wu, Y Lv, F Pan - Ear, Nose & Throat Journal, 2024 - journals.sagepub.com
Background: Tinnitus can severely impair people's quality of life. Stress has been involved in
the pathogenesis of multiform mental disorders. Tinnitus-related annoying symptoms have a …
the pathogenesis of multiform mental disorders. Tinnitus-related annoying symptoms have a …
Optimization of overhead enclosure monitoring software in a rodent model of osteoarthritis
JE Helbling - 2022 - search.proquest.com
Osteoarthritis (OA) is a degenerative joint disease characterized by pain, inflammation, and
decreased range of motion, leading to impaired activities of daily living and reduced quality …
decreased range of motion, leading to impaired activities of daily living and reduced quality …
[HTML][HTML] Neurosteroids: A Promising Next Step Towards Treating Behavioral Disorders
A Ferguson - journals.library.columbia.edu
From alcohol addiction to anxiety, psychological illnesses are pervasive in today's society.
While scientists have long struggled to find effective and sustainable treatment methods …
While scientists have long struggled to find effective and sustainable treatment methods …