Plasticity in animal behaviour relies on the ability to integrate external and internal cues from
the changing environment and hence modulate activity in synaptic circuits of the brain. This …

Decades have now passed since Colin Pittendrigh first proposed a model of a circadian
clock composed of two coupled oscillators, individually responsive to the rising and setting …

The sleep–wake cycle is determined by circadian and sleep homeostatic processes.
However, the molecular impact of these processes and their interaction in different brain cell …

Organisms adapt to seasonal changes in photoperiod and temperature to survive; however,
the mechanisms by which these signals are integrated in the brain to alter seasonal biology …

The circadian clock orchestrates daily changes in physiology and behavior to ensure
internal temporal order and optimal timing across the day. In animals, a central brain clock …

Sleep and circadian rhythm disruptions are frequent comorbidities of Parkinson's disease
(PD), a disorder characterized by the progressive loss of dopaminergic (DA) neurons in the …

For at least two centuries, scientists have been enthralled by the “zombie” behaviors
induced by mind-controlling parasites. Despite this interest, the mechanistic bases of these …

Dissection of neural circuitry underlying behaviors is a central theme in neurobiology. We
have previously proposed the concept of chemoconnectome (CCT) to cover the entire …

Insects from high latitudes spend the winter in a state of overwintering diapause, which is
characterized by arrested reproduction, reduced food intake and metabolism, and increased …

Abstract The Madeira cockroach Rhyparobia maderae is a nocturnal insect and a prominent
model organism for the study of circadian rhythms. Its master circadian clock, controlling …